The latest vacuum photodetector

Yoshizawa, Y.; Takeuchi, J.

doi:10.1016/s0168-9002(96)00954-0

Cited by 27 publications

(7 citation statements)

References 3 publications

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“…2). This small and lightweight photodetector has very low thermal noise at room temperature and a relatively high amplification gain [11]. A highly stable detector, in terms of gain and noise levels, is also required since measurements in animals are likely to last more than 1 h or to be repeated over a long period of time.…”

Section: B the Photodetectormentioning

confidence: 99%

“…According to our detection configuration, the first two contributions were directly minimized by choosing a small-diameter and low-noise PMT [11] and a plastic scintillator of low density (see Sectiont II and [9]). The third source of noise was investigated by immersing a 1-mm-diameter probe without a scintillating tip in the F beaker.…”

Section: A Noise Contributionsmentioning

confidence: 99%

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SIC: an intracerebral radiosensitive probe for in vivo neuropharmacology investigations in small laboratory animals: prototype design, characterization, and in vivo evaluation

Pain

Lanièce

Mastrippolito

et al. 2002

IEEE Trans. Nucl. Sci.

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Several high-resolution tomographs dedicated to small animal imaging are presently under development. However, these devices are limited by two major drawbacks: their cost is high and they require animal anaesthesia and immobilization, thus restricting the scope of investigations. Therefore, we have developed SIC (French acronym for "Sonde IntraCérébrale") a low-cost beta microprobe for measuring local radioactivity in awake, freely moving animals. Besides good sensitivity, SIC offers the advantage of a high temporal resolution, a major asset for in vivo measurements of tracer kinetics. Furthermore, SIC can be readily combined with existing techniques such as electrophysiology, microdialysis, voltammetry and magnetic resonance imaging, providing simultaneous complementary information on cerebral function. We present here the design, manufacture, and evaluation of a SIC prototype. In vitro evaluation using a beaker filled with a homogenous aqueous solution of [ 18 F]-fluorodeoxyglucose ( 18 F-FDG) confirmed our Monte Carlo simulation results in terms of sensitivity and detection volume. Further in vivo studies on rats with two probes implanted in the brain validated the use of SIC to measure the local concentration of radio-labeled molecules in rat brain with a high temporal resolution.Index Terms-Beta detector, in vivo kinetics, intracerebral probe, positrons.

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Section: B the Photodetectormentioning

confidence: 99%

Section: A Noise Contributionsmentioning

confidence: 99%

SIC: an intracerebral radiosensitive probe for in vivo neuropharmacology investigations in small laboratory animals: prototype design, characterization, and in vivo evaluation

Pain

Lanièce

Mastrippolito

et al. 2002

IEEE Trans. Nucl. Sci.

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“…A compact tube like the Hamamatsu Photonics [8] R5900-00-M16 multi-anode photomultiplier (M16) fitted very well into the over-all scheme. The performance of the M16 tube was first reported in [9] and comprehensive tests on gain, uniformity, cross-talk and behaviour in magnetic fields have been conducted by [10]. Since this study, Hamamatsu has continued to make improvements to the tube particularly in quantum efficiency and collection efficiency of the dynode chain.…”

Section: Design Considerationsmentioning

confidence: 99%

Development of a compact scintillator hodoscope with wavelength-shifting fibre read-out

Achenbach

Cobb

Wahl

2005

Nuclear Instruments and Methods in Physics Research Section A:

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We report on the prototyping of a plastic scintillator hodoscope with wavelengthshifting fibre read-out by a multi-anode photomultiplier as part of the development of a detector for cosmic ray muons to be carried aboard an aircraft. Light yield and light attenuation measurements on single-and double-clad wavelength-shifting fibres were performed. Low power, low-threshold, discriminators were designed. A prototype 16-channel hodoscope with two planes was built and tested with cosmic rays. After correcting for geometrical factors a global intrinsic efficiency of ǫ > 98 % was obtained in both planes. The overall performance of the hodoscope proved it to be well suited for the Adler experiment to measure the high altitude muon flux.

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“…HPMTs allow for a finer spatial segmentation than MCPMs but require higher voltages and low noise amplification. In this article we present measurements with a readout system consisting of fibers coupled to small size 16 and 64 channel photomultipliers [7].…”

Section: Introductionmentioning

confidence: 99%