The Lancashire Quality of Life Profile: modification and psychometric evaluation

Nieuwenhuizen, Chijs van; Schene, Aart H.; Koeter, Maarten W. J.; Huxley, Peter

doi:10.1007/s001270050288

Cited by 85 publications

(97 citation statements)

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“…The independent variables were entered in the following steps: sociodemographic variables; age at onset of illness, duration of illness and family history of mental illness; the 5 domains and total scores of the Camberwell Assessment of Need; the 4 caregiving consequences' domains of the Involvement Evaluation Questionnaire; the total Verona Service Satisfaction Scale scores; the positive/negative self-esteem, positive/negative affect from the LQoLP, and the objective QOL indicators of the LQoLP. For the multiple regression data, multicollinearity (i.e., significant correlation between dependent variable and independent variables) was assessed by the values of 'tolerance' (cutoff score ^ 0.2) and variance inflation factor (cutoff score 1 4.0) [50] .…”

Section: Discussionmentioning

confidence: 99%

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Schizophrenia Psychopathology in a Kuwaiti Arab Sample

Zahid

Ohaeri²

2010

Psychopathology

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Background: The heterogeneity of schizophrenia psychopathology has led to a search for symptom clusters that could be related to broad features of the disease. The objectives of the study were to: (1) highlight the pattern of symptoms among Kuwaiti subjects with schizophrenia, using the ICD-10 symptom checklist; (2) assess the factor structure of the Brief Psychiatric Rating Scale 18 (BPRS-18) and BPRS-24, and (3) evaluate the relationship of the resulting factors with sociodemographic characteristics, age at onset of illness, family history of mental illness, objective indicators of quality of life, self-esteem, affect balance, family caregiver burden, patient’s perceptions of service satisfaction and needs for care. Method: Consecutive outpatients in stable condition were assessed with the BPRS and ICD-10 symptom checklist, as well as measures of quality of life, needs for care, service satisfaction and family caregiver burden. Results: There were 130 patients (66.1% men, mean age = 36.8 years, age at onset of illness = 24.2 years, duration of illness = 12.9 years). Of the ICD-10 symptoms, the commonest positive symptoms were hallucinations (58.5%) and delusions (72%). Catatonic symptoms were rare (2.9%). About a quarter of the subjects experienced 4 of the negative symptoms. In exploratory factor analysis, we broadly replicated the known syndromes for BPRS-24 (disorganization, positive, activation, manic, negative and depression) and BPRS-18 (negative, positive, activation and affect). In regression analyses, the variables independently associated with psychopathology were family income, negative affect, self-esteem, duration of illness, age, lack of money for enjoyment, met needs for care and caregiver tension. The negative syndrome had more significant associations with the variables investigated than the positive syndrome. Psychopathological scores were separable from indices of psychological well-being. Conclusion: In this first study of schizophrenia psychopathology from the Arab world, the clinical manifestations were similar to the data from the developed countries. The persistence of psychotic symptoms despite freely available antipsychotic treatment and the impact on caregiver burden call for attention to the perennial issue of treatment resistance and underscore the need for continued interaction with family members after the acute inpatient phase of treatment, in order to address the impact of symptoms.

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Section: Discussionmentioning

confidence: 99%

“…It is one of the most widely used instruments for the assessment of QOL in schizophrenia research [50] . The LQoLP was developed from Lehman's Quality of Life Interview [51] , combining objective and subjective measures in several life domains.…”

Section: Lqolp-eumentioning

confidence: 99%

Schizophrenia Psychopathology in a Kuwaiti Arab Sample

Zahid

Ohaeri²

2010

Psychopathology

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“…As an outcome measure for group comparisons, the Lancashire Quality of Life Profile, which covers a large number of different areas, has proved to be a valid instrument for the evaluation of medical and social interventions [40,41] . Due to the fact that not all life-satisfaction scales (e.g.…”

Section: Methodsmentioning

confidence: 99%

Quality of Life in Patients Receiving Opioid Maintenance Therapy

et al. 2008

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Background/Aims: In recent years, quality of life (QoL) assessments have proved useful for evaluating and comparing drug treatment programs. To compare QoL of patients maintained on methadone versus slow-release morphine, a prospective, randomized, double-blind, double-dummy, cross-over study was conducted. Methods: Over two 7-week study phases, participants received either oral slow-release morphine capsules followed by methadone oral solution or vice versa. QoL status was assessed at baseline, week 7, and week 14 using the German version of the Lancashire Quality of Life Profile. Results: No statistically significant difference was found between methadone and slow-release morphine in any QoL domain. A significant time effect for nearly all QoL domains was observed after 14 weeks of opioid medication, independent of the chosen drug (general well-being, p < 0.001; mental health, p = 0.001; general state of health, p = 0.018; leisure time at home, p = 0.034; leisure time out of the home, p = 0.008). Furthermore, this study revealed that even short-term maintenance yields significantly higher QoL scores in the important domain of general well-being. Conclusion: These results indicate that slow-release morphine has effects comparable to methadone on patient-reported QoL data and is thus a promising option for treatment of opioid-dependent subjects.

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“…in all Scandinavian languages, German, Dutch, Italian, Chinese) have been developed following a common methodology [30][31][32]. It has proved to be psychometrically valid, reliable and responsive to changes over a wide range of QOL and health statuses, as well as appropriate for the evaluation of medical and social interventions as an outcome measure for group comparisons [30][31][32].…”

Section: Methodsmentioning

confidence: 99%

Gender Differences in Health-Related Quality of Life on Admission to a Maintenance Treatment Program

et al. 2005

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We compared the gender differences in health-related quality of life (QOL) on admission to a maintenance program. 103 opioid users (65 men and 38 women) admitted to a maintenance treatment program during 2000–2002 were studied. During this period we assessed the QOL status using the German version (‘Berlin Quality of Life Profile’) of the Lancashire Quality of Life Profile. Physical symptoms were measured using the Opioid Withdrawal Scale. 312 urine screening tests were carried out to evaluate consumption. The female group showed significantly less additional consumption of other opiates (p = 0.043) compared with the male group. The male group showed significantly better QOL scores in self-esteem (p = 0.015), psychical health (p = 0.027), and law and security (p = 0.008). The outcome measures for withdrawal scores showed significantly less symptoms for males in twitching of muscles (p = 0.034), vomiting (p = 0.002), depressions (p = 0.004) and poor appetite (p = 0.008). In summary, both genders showed only a few significant differences on admission in terms of QOL and physical symptoms. The predominant effects of drug use appear to eclipse the gender-related role pattern. Further exploration of gender and QOL could have important theoretical and treatment implications.

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The Lancashire Quality of Life Profile: modification and psychometric evaluation

Cited by 85 publications

References 0 publications

Schizophrenia Psychopathology in a Kuwaiti Arab Sample

Schizophrenia Psychopathology in a Kuwaiti Arab Sample

Quality of Life in Patients Receiving Opioid Maintenance Therapy

Gender Differences in Health-Related Quality of Life on Admission to a Maintenance Treatment Program

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