1936
DOI: 10.2307/209714
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The Lakes of Potosi

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Cited by 8 publications
(13 citation statements)
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“…The 26-kD type II transmembrane TNF precursor protein, expressed on many cell types, is proteolytically converted into a soluble 52-kD homotrimer (6). An elevated serum level of TNF is associated with the pathophysiology of rheumatoid arthritis (RA), inflammatory bowel disease, and ankylosing spondylitis (1,7,8), and molecules that inhibit TNF signaling have demonstrated clinical efficacy in treating some of these diseases (9,10).…”
mentioning
confidence: 99%
“…The 26-kD type II transmembrane TNF precursor protein, expressed on many cell types, is proteolytically converted into a soluble 52-kD homotrimer (6). An elevated serum level of TNF is associated with the pathophysiology of rheumatoid arthritis (RA), inflammatory bowel disease, and ankylosing spondylitis (1,7,8), and molecules that inhibit TNF signaling have demonstrated clinical efficacy in treating some of these diseases (9,10).…”
mentioning
confidence: 99%
“…Mining joins grazing pressure, farmland expansion, road construction, and urbanization as serious causes of long-term environmental degradation in highland southern Bolivia (Brandt and Townsend 2006). Potosí has endured water shortages throughout its history and local streams are key resources in the arid, high-altitude, low-productivity landscape (Rudolf 1936). Downstream, contamination limits the uses of Rio Pilcomayo.…”
Section: Introductionmentioning
confidence: 99%
“…Water resources in and around the city of Potosí (estimated population 150,000) have been dramatically and continuously impacted geomorphologically, geochemically, and ecologically by human activities since the initiation of mining. First, a system of artificial lakes was constructed in the Kari-Kari region, east of the city to provide drinking water and hydropower for ore processing (Rudolf 1936). Concurrently, the Ribera de la Vera Cruz was constructed through the city with a system of 32 dams to power the waterwheels of over a hundred ore processers or ingenios (Rudolf 1936;García-Guinea 1995).…”
Section: Introductionmentioning
confidence: 99%
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