The Karlsruhe Heart Model KaHMo: A modular framework for numerical simulation of cardiac hemodynamics

Schenkel, Torsten; Krittian, Sebastian; Spiegel, K.; Höttges, Stefan; Perschall, Markus; Oertel, Herbert

doi:10.1007/978-3-642-03882-2_163

Cited by 6 publications

(7 citation statements)

References 25 publications

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“…Numerous studies on fluid–structure‐coupled simulation of the heart flow by CFD performed by biomedical engineers have also shown the beneficial effects of the elliptical LV geometry in terms of blood flow mechanics . The Karlsruhe Heart Model has also been used to show the relationship between fluid–structure interaction and geometry model . Baretti et al.…”

Section: Discussionmentioning

confidence: 99%

Congenital Left Ventricular Outpouchings: A Systematic Review of 839 Cases and Introduction of a Novel Classification after Two Centuries

2014

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Section: Discussionmentioning

confidence: 99%

Congenital Left Ventricular Outpouchings: A Systematic Review of 839 Cases and Introduction of a Novel Classification after Two Centuries

2014

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“…Fluent is used for this part of the study as the VAD and the hemolysis prediction is to be implemented as part of a modular model of human heart flow (16,17) using Fluent for the flow simulation. This model is based on tetrahedral grids with grid motion (18).…”

Section: Methodsmentioning

confidence: 99%

The Progressive Wave Pump: Numerical Multiphysics Investigation of a Novel Pump Concept With Potential to Ventricular Assist Device Application

Perschall

Drevet

Schenkel³

et al. 2012

Artificial Organs

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This article describes the numerical fluid–structure interaction (FSI) validation of a new pumping concept and the possibility for application of a further developed type, as an implantable ventricular assist device (VAD). The novel principle of the so‐called progressive wave pump is based on the interaction of an elastic membrane actuated by forced excitation with a surrounding fluid and the pump housing. By applying forced vibrations to one end of the membrane, a transversal wave builds up and progresses to the far end generating both a positive pressure gradient and flow rate. Among others, two axisymmetric geometrical configurations are possible, namely the discoidal and the tubular design. The first one has been built as a physical prototype and is experimentally investigated. In addition, a corresponding numerical FSI model is set up and validated against the experimental findings. Based on this validated numerical method, further numerical investigations are conducted focusing on the development of a tubular progressive wave pump concept with regard to its potential for application as a VAD in the future. To address VAD‐relevant issues such as size, hydraulic performance, and blood trauma, corresponding numerical simulations involving macroscopic blood trauma models have been performed. Although being still in an early phase of development, the results are promising and indicate that the wave pump concept in its present state is feasible and can be further developed and investigated as a new type of blood pump.

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“…In Gl. (1) fließen neben I 0 (k) und I Nanocom (k) noch die Volumenkonzentration der Teilchen n, die optische Weglänge L, und die Teilchengrößenverteilung p(r, q, r) mit ein, die von der Partikelgröße r und den beiden Verteilungsparametern q und r abhängt [10].…”

Section: Physikalische Grundlagenunclassified

“…(4)). Bei der Bildung dieses Quotienten kürzen sich die Weglänge L und die Teilchendichte n heraus [10,16,17]. Man erhält den so genannten Dispersionsquotienten DQ:…”

Section: Physikalische Grundlagenunclassified

Online Measurement Method for Characterization of Nanocomposites

Guschin

Becker

Eisenreich

et al. 2012

Chemie Ingenieur Technik

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By the incorporation of nanoparticles into a polymer matrix the properties of the nanocomposites can be significantly improved compared to the starting polymer. As the incorporation process appears to be challenging due to possible agglomeration of the nanoparticles it is very important to control it online. In this research, transparent SiO 2-polypropylene(PP) nanocomposite was examined with the optical turbidimetric method directly at the extruder. Furthermore, comparative scanning electron microscopy measurements are presented. It is shown that the turbidimetric analysis can be used for online quality control of nanocomposites

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The Karlsruhe Heart Model KaHMo: A modular framework for numerical simulation of cardiac hemodynamics

Cited by 6 publications

References 25 publications

Congenital Left Ventricular Outpouchings: A Systematic Review of 839 Cases and Introduction of a Novel Classification after Two Centuries

Congenital Left Ventricular Outpouchings: A Systematic Review of 839 Cases and Introduction of a Novel Classification after Two Centuries

The Progressive Wave Pump: Numerical Multiphysics Investigation of a Novel Pump Concept With Potential to Ventricular Assist Device Application

Online Measurement Method for Characterization of Nanocomposites

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