The Journey to Clonal Hematopoiesis and Applications Incardiovascular Disease and Cancer
Santiago Redondo,
Jaime Perez de Oteyza
Abstract:: For a long time, atherosclerosis has been regarded as a mere lipid deposit in the blood vessels. However, in the recent years a growing body of experimental and clinical evidence have highlighted the role of inflammation and immunity as a central mechanism of disease. Moreover, in the last decade the coming of next-generation sequencing and its application to large human population has broken the barrier between inflammation and cancer. Indeed, acquired mutation in key genes related to the control of hematop… Show more
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