The items in the Chinese version of the Montreal Cognitive Assessment Basic discriminate among different severities of Alzheimer’s disease

Zhang, Yan-rong; Ding, Yun-Long; Chen, Keliang; Liu, Yan; Wei, Can; Zhai, Ting-ting; Wang, Wen‐Juan; Dong, Wanli

doi:10.21203/rs.2.10497/v2

Cited by 13 publications

(17 citation statements)

References 12 publications

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“…In contrast, the part B subset of the Trail Making test was correctly performed by only 37% of people with an elementary-level education, and <30% of individuals with an elementary-level education and 7% of illiterate individuals correctly completed cube drawing (Gómez et al, 2013 ). Similarly, studies using MoCA in populations of Brazilian (Apolinario et al, 2018 ), Turkish (Yancar and Öscan, 2015 ), and Chinese (Zhang et al, 2019 ) origin have reported the influence of education level on MoCA cut-off points. A systematic review on the cultural validity of MoCA (O'Driscoll and Shaikh, 2017 ) and a critical review on BCS for older adults with low levels of education (Tavares-Júnior et al, 2019 ) suggest different cut-off points of MoCA according to education level.…”

Section: Discussionmentioning

confidence: 91%

Systematic Review of the Diagnostic Validity of Brief Cognitive Screenings for Early Dementia Detection in Spanish-Speaking Adults in Latin America

Custodio

Duque²,

Montesinos

et al. 2020

Front. Aging Neurosci.

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The aim of this study was to evaluate the validity of brief cognitive screening (BCS) tools designed to diagnose mild cognitive impairment (MCI) or dementia in Spanish-speaking individuals over the age of 50 years from Latin America (LA). Methods: A systematic search of titles and abstracts in Medline, Biomed Central, Embase, Scopus, Scirus, PsycINFO, LILACS, and SciELO was conducted. Inclusion criteria were papers written in English or Spanish involving samples from Spanish-speaking Latin American individuals published until 2018. Standard procedures were applied for reviewing the literature. The data related to the study sample, methodology, and procedures applied, as well as the performance obtained with the corresponding BCS, were collected and systematized. Results: Thirteen of 211 articles met the inclusion criteria. The studies primarily involved memory clinic-based samples, with the exception of two studies from an adult day-care center, one from a primary care clinic, and one from a community-based sample. All the studies originated from five of the 20 countries of LA and all used standardized diagnostic criteria for the diagnosis of dementia and MCI; however, the diagnostic protocols applied differed. Most studies reported samples with an average of 10 years of education and only one reported a sample with an average of <5 years of education. No publication to date has included an illiterate population. Although the Montreal cognitive assessment (MoCA) is the most widely-used BCS tool in LA, it is significantly influenced by education level. Conclusions: Although evidence is still limited, the findings from studies on LA populations suggest that MoCA requires cultural adaptations and different cutoff points according to education level. Moreover, the diagnostic validity of the INECO frontal Custodio et al. Brief Cognitive Screenings to Dementia in Latin-America screening (IFS) test should be evaluated in populations with a low level of education. Given the heterogeneity that exists in the levels of education in LA, more studies involving illiterate and indigenous populations are required.

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Section: Discussionmentioning

confidence: 91%

Systematic Review of the Diagnostic Validity of Brief Cognitive Screenings for Early Dementia Detection in Spanish-Speaking Adults in Latin America

Custodio

Duque²,

Montesinos

et al. 2020

Front. Aging Neurosci.

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“…The neuropsychological tests were all designed by the Hong Kong University and Anhui Medical University [25], except MoCA. The Beijing Version of the Montreal Cognitive Assessment Test (MoCA) was administered to assess global cognitive function [26]. An adjusted MoCA score < 26 was considered cognitive impairment.…”

Section: Neuropsychological Backgroundmentioning

confidence: 99%

Changes in Spatial Working Memory in Stable Chronic Obstructive Pulmonary Disease: A Retrospective Study

Jiang

et al. 2020

BioMed Research International

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Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow limitation and is often accompanied by cognitive impairment. Little is known about the working memory of COPD patients. The aim of the study is to evaluate the spatial working memory of COPD patients using the classical visuospatial working memory neuropsychological paradigms. This was a retrospective study of patients with COPD who were evaluated for neurocognitive functions between February and December 2018 at Hefei Second People’s Hospital. Healthy controls (HC) were included. The neuropsychological tests included the Beijing Version of the Montreal Cognitive Assessment Test (MoCA), digit span test (DS), Chinese Auditory Verbal Learning Test (CAVLT), Stroop test, and Verbal Fluency Test (VFT). The COPD group performed worse in MoCA (22.3±4.5 vs. 26.1±2.9, P<0.001), Stroop interference test (44.2±16.9 vs. 36.8±10.3, P=0.038), and VFT (12.9±2.8 vs. 15.3±4.7, P=0.021) vs. the HC group. Compared with the HC group, COPD patients had statistically significant differences with respect to 0-back RT (657±46 vs. 578±107, P=0.001), 1-back accuracy (41.8±12.1% vs. 81.5±18.1%, P<0.001), 1-back RT (592±75 vs. 431±138, P<0.001), 2-back accuracy (31.4±9.9% vs. 68.1±16.6%, P<0.001), and 2-back RT (563±79 vs. 455±153, P=0.002). Only PaO2 was independently associated with 0-back RT (B=0.992±0.428, P=0.028) and 1-back ACC (B=0.003±0.001, P=0.004). COPD patients exhibit impairment in working memory and executive function, but not in short- or long-term memory. The impairment of working memory in a patient with COPD may be more due to integrate memory information rather than to memory information storage. COPD patients exhibit a frontal-type cognitive decline.

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“…Unfortunately, only 86% cases could be correctly identified as either normal or MCI [7]. Recent studies in mainland China suggested that the cutoffs for MCI were 24 in a clinical sample [8] and ranged from 18 to 25 in normative samples [9][10][11]. ese studies suggested that the cutoffs were contingent upon sampling (i.e., normative versus clinical), age, education, cultural background, and validating criteria [12].…”

Section: Introductionmentioning

confidence: 99%

Montreal Cognitive Assessment: Seeking a Single Cutoff Score May Not Be Optimal

Yang

Dong

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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Background. Cutoff scores of the Montreal cognitive assessment (MoCA) for screening mild cognitive impairment in older adults differ across the world and within the Chinese culture. It is argued that to seek a cutoff score is essential to classify test participants. It was unknown how taking a classifying approach might reveal the cutoff score for identifying mildly cognitively impaired older adults. Methods. Participants, selected from 13 communities in Wuhan, China, were tested with the Chinese version of MoCA and rated with the Activities of Daily Living and the Clinical Dementia Rating scales. Mixture modeling was applied to the data with certain covariates and MoCA sum scores as the outcome of the latent class. Models with different numbers of classes were compared in terms of information criteria, likelihood ratio test, entropy, and interpretability. Results. A 3-class model (normal, mildly impaired, and severely impaired) was found to fit the data best. The normal class averaged a MoCA score of 24, while the severely impaired class averaged a score below 18. For those cases with MoCA scores above 18 and below 24, it is not certain if they are in the normal or the severely impaired classes. Conclusion. Latent variable classification modeling provides another option to identify MCI in older adults. Some categorically different cases of MCI cannot be captured with any single MoCA sum score. A range of 18–24 MoCA scores might serve as a better screening criterion of MCI. Older adults who scored within this gray zone should be monitored for potential interventions.

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The items in the Chinese version of the Montreal Cognitive Assessment Basic discriminate among different severities of Alzheimer’s disease

Cited by 13 publications

References 12 publications

Systematic Review of the Diagnostic Validity of Brief Cognitive Screenings for Early Dementia Detection in Spanish-Speaking Adults in Latin America

Systematic Review of the Diagnostic Validity of Brief Cognitive Screenings for Early Dementia Detection in Spanish-Speaking Adults in Latin America

Changes in Spatial Working Memory in Stable Chronic Obstructive Pulmonary Disease: A Retrospective Study

Montreal Cognitive Assessment: Seeking a Single Cutoff Score May Not Be Optimal

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