The Italian Brain Normative Archive of structural MR scans: norms for medial temporal atrophy and white matter lesions

Abstract

Persons in the IBNA study had clinical and neuropsychological features consistent with that of the general population. Their brain morphometric features may be used as normative references for patients with suspected neurodegenerative disorders.

Assessment of white matter tract damage in mild cognitive impairment and Alzheimer's disease

“…In both AD (P < 0.001) and aMCI patients (P < 0.001), hippocampal volumes were decreased compared with that of a reference healthy elderly population [Galluzzi et al, 2009]. The individual mean hippocampal volumes were 1.5 SDs below the mean hippocampal volume of the reference group in 19/25 AD and 8/18 …”

“…An experienced radiologist reviewed the severity of the cerebrovascular disease according to the Wahlund rating scale [Wahlund et al, 2001]. Subjects were excluded when the Wahlund rating scale was above the 90th percentile of the distribution from a previously published healthy elderly population [Galluzzi et al, 2009]. The local ethics committee approved the study.…”

Impact of alcohol consumption in healthy adults: A magnetic resonance imaging investigation

“…As for the specific reasons for MRI referral for the patients in this sample, past clinical history analyses showed that those reasons were not unevenly related to specific sociodemographic variables, global cognition, depressive symptoms or other clinical features (Galluzzi et al, 2009).…”

“…The imaging acquisition was carried out at the Neuroradiology Unit of the "Città di Brescia" Hospital, Brescia (Italy), from March 2001 to December 2008, and includes data from outpatients examined for reasons unrelated to cognition (Riello et al, 2005;Galluzzi et al, 2009).…”

“…This paper summarizes data on a normative dataset of brainimaging scans taken from people who were determined to be free of neurological disorders or impairment and who did not meet diagnostic criteria for any current mental disorder (Riello et al, 2005;Galluzzi et al, 2009). Alcohol and substance use was assessed in this group of people through a detailed interview.…”