The iron wheel of parasite life cycles: Then and now!

Bolek, Matthew G.; Stigge, Heather A.; Gustafson, Kyle D.; Janovy, John; Esch, Gerald W.

doi:10.1002/9781118884799.ch9

Cited by 8 publications

(2 citation statements)

References 36 publications

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“…When a frog (or toad) eats a dragonfly or damselfly and if that odonate has cercaria, the parasite makes its way through the esophagus and lodges in the lungs within 5 days. Once the lung fluke is located in its definitive host, the life cycle of H is complete ( 3 ). In its natural habitat, Rana pipiens is an opportunistic feeder, eating a variety of invertebrates including ants, beetles, and dragonflies.…”

Section: Introductionmentioning

confidence: 99%

Hematoloechus sp. attachment shifts endothelium in vivo from pro- to anti-inflammatory profile in Rana pipiens: evidence from systemic and capillary physiology

Williams

Flood

2023

American Journal of Physiology-Regulatory, Integrative and Comp

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This prospective, descriptive study focused on lung flukes (Haematoloechus sp., H) and their impact on systemic and individual capillary variables measured in pithed Rana pipiens, a long-standing model for studies of capillary physiology. Three groups were identified based on H attachment: no Haematoloechus (No H), Haematoloechus not attached (H Not Att), and Haematoloechus attached (H Att). Among 38 descriptive, cardiovascular, and immunological variables, 18 changed significantly with H. Symptoms of H included weight loss, elevated immune cells, heart rate variability, faster coagulation, lower hematocrit, and fluid accumulation. Important capillary function discoveries included median baselines for hydraulic conductivity (Lp) of 7.0 (No H), 12.4 (H Not Att), and 4.2 (H Att) x 10-7 cm.s-1.cm H2O-1(P<0.0001) plus seasonal adaptation of sigma delta pi (s(pc - pi), P=0.03). Pro- and anti-inflammatory phases were revealed for Lp and plasma nitrite/nitrate concentration ([NOx]) in H Not Att and H Att and capillary wall tensile strength increased in H Att. H attachment was advantageous for the host due to lower edema and for the parasite via a sustained food source illustrating an excellent example of natural symbiosis. However, H attachment also resulted in host weight loss: in time, a conundrum for the highly dependent parasite. The study increases overall knowledge of Rana pipiens by revealing intriguing effects of H and previously unknown, naturally occurring seasonal changes in many variables. The data improve Rana pipiens as a general scientific and capillary physiology model. Diseases of inflammation and stroke are among the clinical applications.

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Section: Introductionmentioning

confidence: 99%

Hematoloechus sp. attachment shifts endothelium in vivo from pro- to anti-inflammatory profile in Rana pipiens: evidence from systemic and capillary physiology

Williams

Flood

2023

American Journal of Physiology-Regulatory, Integrative and Comp

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“…Canada, Field Survey, Gyraulus, Life Cycle Variation, New Host Records, Promenetus Understanding the life cycles of helminth parasites is essential to establishing their host specificity, geographic range, and transmission. However, most helminth life cycles have not been elucidated or if they have, they have been revised as more life history studies of the parasite have been completed (Bolek et al, 2016). One reason for these revisions is that many life cycle descriptions are based on field collections in 1 part of the entire range of the parasite.…”

Section: Introductionmentioning

confidence: 99%

Broader Geographic Sampling Increases Extent of Intermediate Host Specificity for a Trematode Parasite (Notocotylidae: Quinqueserialis quinqueserialis)

Gagnon

Detwiler

2019

Journal of Parasitology

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Broader geographic sampling increases extent of intermediate host specificity for a trematode parasite (Notocotylidae: Quinqueserialis quinqueserialis) --Manuscript Draft--Manuscript Number: 19-16R2 Full Title: Broader geographic sampling increases extent of intermediate host specificity for a trematode parasite (Notocotylidae: Quinqueserialis quinqueserialis) Short Title: Broader geographic sampling reveals novel hosts Article Type: Short Communications

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