“…Carbodiimide-mediated incorporation of p-aminophenyl glycosides was the basis for the establishment of a non-radioactive, rapid and sensitive assay, which has extended application beyond lectinology in other branches of receptor analysis (S. . By means of¯uorescence microscopy the speci®c binding of carbohydrates to spermatozoa has been detected (Sinowatz et al, 1988(Sinowatz et al, , 1989, thereby supporting the hypothesis that glycan recognition plays an important role in mammalian fertilization (Shalgi and Raz, 1997;Sinowatz et al, 1997Sinowatz et al, , 1998McLeskey et al, 1998;Dell et al, 1999;Takasaki et al, 1999;Wassarman, 1999;Hirohashi and Lennarz, 2000). These studies have also detected binding sites which mediate cell adhesion to a matrix presenting the appropriate carbohydrates (S. Wawotzny et al, 1995).…”