The Investigation of the Recurrence Rate of Cholesteatoma Using Kaplan-Meier Survival Analysis

Abstract

Kaplan-Meier survival analysis should be used for calculating the recurrence rate of cholesteatoma. Although this analytic method further demonstrates that CWDT is a more reliable surgical method than ICWT/CWR in reducing cholesteatoma recurrence, clinical judgment should be exercised, and we continue to recommend that a flexible approach should be adopted in deciding whether to perform CWDT or ICWT/CWR for individual cases.

Pediatric Cholesteatoma Surgery Using a Single-Staged Canal Wall Down Approach

“…previously published work in which he recommended the standardized use of survival analysis for long-term data of five or more years and cut-off analyses at 12 months for postoperative otorrhea and hearing outcomes (8). Other authors support this and discuss the importance of using Kaplan-Meier survival analysis when discussing recidivism rates in cholesteatoma as the number of censored cases inevitably increases with observation time (4,9,10).…”

Acquired cholesteatoma pathogenesis: stepwise explanations

“…It is argued that recurrent bouts of chronic infection contribute to cholesteatoma persistence and recurrence. 8,15,21,22,53,54 Pathological mechanisms The pathological mechanisms encountered in precholesteatoma and cholesteatoma conditions can be summarised as follows.…”

Cost analysis and outcomes of a second‐look tympanoplasty‐mastoidectomy strategy for cholesteatoma

“…A mastoidectomy can be completed with either a canal wall‐down or canal wall‐up technique. Reported advantages of the canal wall‐down technique include superior exposure of the middle ear and lower disease recurrence rates . Advantages of the canal wall‐up technique include preserved or improved hearing outcomes, preservation of the natural external ear canal wall, tympanic membrane position, and avoidance of a mastoid cavity .…”

“…Reported advantages of the canal wall-down technique include superior exposure of the middle ear and lower disease recurrence rates. [1][2][3] Advantages of the canal wall-up technique include preserved or improved hearing outcomes, preservation of the natural external ear canal wall, tympanic membrane position, and avoidance of a mastoid cavity. 4,5 However, the canal wall-up technique has a reported higher risk of residual and recurrent cholesteatoma.…”