The Investigation of the Chemical Composition and Applicability of Gold Nanoparticles Synthesized with Amygdalus communis (Almond) Leaf Aqueous Extract as Antimicrobial and Anticancer Agents

Baran, Mehmet Fırat; Keskin, Cumali; Baran, Ayşe; Eftekhari, Aziz; Omarova, Sabina; Khalilov, Rovshan; Adican, Mehmet Tevfik; Rosić, Gvozden; Selaković, Dragica; Yildiztekin, Mahmut; Kurt, Kadri; Ava, Canan Aytuğ; Atalar, Mehmet Nuri

doi:10.3390/molecules28062428

Cited by 11 publications

(9 citation statements)

References 53 publications

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“…64 In the current investigation, HE plant extract was used as a capping, stabilizing, and reducing mediator in the synthesis of AuNPs. Similar results were also reported by Baran et al 65…”

Section: Uv Analysissupporting

confidence: 92%

Heliotropium eichwaldi‐functionalized gold nanoparticles synthesis, characterization, and biological activities

Sher,

Ahmed,

Mushtaq

2024

Applied Organom Chemis

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Nanoparticles (NPs) are the essential building block of nanotechnology; they have a wide range of biomedical applications. In comparison with chemical methods, green synthesis is significant because of their non‐toxicity, eco‐friendliness, and simplicity; thus, the plant extracts are useful in the biogenic synthesis of NPs. In this study, Heliotropium eichwaldi‐induced gold NPs (HE‐AuNPs) were produced. These HE‐AuNPs were afterward examined using UV–vis spectroscopy, FTIR, SEM, XRD, and EDX analysis. The XRD analysis authorized the crystalline structure of AuNPs with an average size of 11.11 nm for four peaks (38.31°, 44.39°, 64.76°, and 77.65°), the SEM analysis displayed the elongated sphere‐shaped morphologies of HE‐AuNPs with 20 nm size, and the EDX analysis revealed that Au (44.33%) was the main element of AuNP. The FTIR analysis confirmed the presence of various coating and reducing organic molecules. In comparison with HE extract and hydrogen tetrachloroaurate (III) trihydrate (HAuCl4.3H2O) solution, the AuNPs showed outstanding inhibitory activity against free radicals, ‐amylase, and AChE. Our work suggests the successful generation of HE‐AuNPs, subsequently significant antioxidant, antidiabetic, and anti‐Alzheimer agents. However, further study is suggested to minimize potential risks.

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“…64 In the current investigation, HE plant extract was used as a capping, stabilizing, and reducing mediator in the synthesis of AuNPs. Similar results were also reported by Baran et al 65…”

Section: Uv Analysissupporting

confidence: 92%

Heliotropium eichwaldi‐functionalized gold nanoparticles synthesis, characterization, and biological activities

Sher,

Ahmed,

Mushtaq

2024

Applied Organom Chemis

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“…The EDX spectrum of AD-AgNPs verified the incidence of sharp spectral signals at nearly 3 keV for the absorption of nanocrystals in the silver area owing to surface plasmon resonance (Figure 2). This characteristic peak (3 keV) is consistent with the results of many studies with different plants (Hatipoğlu, 2022b;Ali et al, 2023;Baran et al, 2023). Other absorption peaks that emerged were due to phytochemicals in A. dioscoridis leaf extract.…”

Section: Edx Analysissupporting

confidence: 90%

Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties

İpek

Baran

Yıldız

et al. 2023

International Journal of Agriculture Environment and Food Sciences

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This study was carried out to synthesize silver nanoparticles (AgNPs) from Arum dioscoridis (AD) leaf extract and to investigate the cytotoxic and antipathogenic effects of them. The plant material had a reducing and stabilizing effect on the synthesized nanomaterial. During the plant-mediated synthesis of nanomaterials, no substances that would cause environmental pollution were used. For the structural characterization of AD-AgNPs, Ultraviolet-visible (UV-vis) Spectroscopy, Field Emission Scanning Electron Microscopy (FE-SEM), Electron Dispersive X-ray (EDX) Spectroscopy, Fourier Transform Infrared (FT-IR) Spectroscopy, Transmission Electron Microscopy (TEM), X-ray Diffractometer (XRD), Atomic Force Microscopy (AFM) and Zetasizer analyses were performed. The produced AgNPs showed maximum surface plasmon resonance at 431.67 nm and had mostly spherical morphology. The zeta potential value of the nanomaterial was -9.76 mV and the average powder crystal size was 31.48 nm. The minimum inhibitory concentration (MIC) values (mg/L) of AD-AgNPs on Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, and Candida albicans were 0.25, 2.00, 0.125, 4.00, and 1.00, respectively. After 24 and 48 hours of application by MTT [3-(4,5-dimetiltiazol-2-il)-2,5-difeniltetrazolium bromid] assay, the half-maximal inhibitory concentrations (IC50: μg/mL) of AD-AgNPs on human colon adenocarcinoma cell (CACO-2), human breast cancer cell (MCF-7), glioblastoma multiforme cell (T98-G), and healthy human umbilical vein endothelial cell (HUVEC) lines were determined as 2.977, 2.801, 5.694, 4.392; 2.115, 2.300, 2.612, 4.091, respectively.

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“…The studied strains were resistant to the biogenic AgNPs' antibacterial and anticandidal effects. and a greater range of species (21,(26)(27)(28). But it…”

Section: Discussionmentioning

confidence: 99%

Green Synthesis of Silver Nanoparticles Using Safran (Crocus sativus) Purple flower and Their Antimicrobial activity

2023

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Objective: In this study, CS-AgNPs were synthesized, characterized, and antimicrobial activity evaluated by using the extract obtained from the purple flower parts of the waste saffron flower with an economical, easy and environmentally friendly method. Method: In this study, green, economical and rapid synthesis of silver nanoparticles (AgNPs) was carried out using Saffron (Crocus sativus (CS)) purple flower extract. For structure elucidation of silver nanoparticles synthesized with saffron flower extract (CS-AgNPs); UV-visible (UV-vis.) Spectrophotometer, Fourier Scanning Electron Microscope (FE-SEM), Scanning Electron Microscope (SEM), Electron Distributed X-rays (EDX), Fourier Transform Infrared Spectroscopy (FT-IR), X-Ray Characterized using Diffraction Diffractrometer (XRD), Transmission Electron Microscope (TEM), Zeta potential data. It was determined that the UV-visible spectrum of the biologically synthesized silver nanoparticles, the spectrum taken after 15 minutes was formed at the maximum wavelength of 405.68 nm. In addition, it was observed that the UV spectrum of the synthesized nanoparticles, taken one month later, gave the same wavelength, and the obtained nanoparticles were stable. Antimicrobial activities of CS-AgNPs were evaluated on gram-positive, gram-negative and fungal strains using the minimum inhibition concentration technique. Results: As a result, it was determined that the obtained CS-AgNPs showed activity on bacterial and fungal strains. Conclusion: It was observed that the smaller the size of the silver nanoparticles obtained, the greater their antimicrobial activity and strong antibacterial and anticandidal activity even at very low concentrations.

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The Investigation of the Chemical Composition and Applicability of Gold Nanoparticles Synthesized with Amygdalus communis (Almond) Leaf Aqueous Extract as Antimicrobial and Anticancer Agents

Cited by 11 publications

References 53 publications

Heliotropium eichwaldi‐functionalized gold nanoparticles synthesis, characterization, and biological activities

Heliotropium eichwaldi‐functionalized gold nanoparticles synthesis, characterization, and biological activities

Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties

Green Synthesis of Silver Nanoparticles Using Safran (Crocus sativus) Purple flower and Their Antimicrobial activity

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