The Investigation of 14 Appendiceal Mucocele Cases Encountered in 4850 Appendectomy Patients

Recommendation of the Peritoneum Neoplasms Service of ``Hospital Santa Rita Da Santa Casa De Misericordia`` at Porto Alegre – Cecal Appendix Mucocele – Laparoscopic or Laparotomical Approach?

“…Furthermore, the most feared complication of appendix mucocele is Pseudomyxoma peritonei, which is a pathology that develops insidiously and can take decades for the formation of symptomatic mucinous ascites. 3,12,19 .…”

“…Considering 1) impossibility of predicting the histology associated with appendiceal mucocele (up to a quarter have associated malignancy) 3,11 , 2) catastrophic abdominal complication if peritoneal dissemination of malignancy 25 , 3) lack of knowledge of cellular behavior exposure to CO2 and pneumoperitoneum, 4) biological plausibility of increased cellular aggressiveness seen in other tumors 20,24 5) Existing scarce and low-quality evidence makes it impossible to consider laparoscopic appendectomy oncologically safe, despite being technically feasible.…”

“…The radiological aspects of these changes do not correlate with histology, unlike other neoplasms. 2,3 . They range from appendix cystadenoma, accumulation of transient intraluminal secretion due to fecality, adenomas, benign neoplasia and malignant neoplasm.…”

“…10 . In up to 20% of cases of appendiceal mucocele, there may be an associated malignant neoplasm 3,11 . In some situations, intraluminal cellular and mucinous content may leak into the abdominal cavityduring surgical manipulation, for example -, evolving into a serious and lethal clinical condition called Pseudomyxoma Peritoneal.…”

Appendiceal mucocele pathologically classified as appendiceal epithelial hyperplasia and preoperatively diagnosed by contrast-enhanced ultrasonography: A case report

“…Preoperative diagnosis can be difficult because the symptoms are similar to those of acute appendicitis. Some reports have shown that transabdominal ultrasonography (US) is useful for preoperative diagnosis of an appendiceal mucocele [2] , [3] , [4] , [5] , [6] , [7] . In patients with appendiceal diseases detected by transabdominal US, the detection rate of appendiceal mucocele was 6.6% [4] .…”