EXPERIMENTAL WORK. (a) The Effect of Raising the Pressure in the Renal Veins onWater-diuresis in Dogs. It has been shown that if the pressure in the renal veins of the dog be raised above the normal by about 4 mm. Hg. albumin appears in the urine [Theobald, 1931]. The technique there adopted was to constrict the inferior vena cava above the point of entry of the renal veins by means of a ligature threaded through a portion of gum-elastic catheter. Results of experiments performed on a bitch, which had previously been perineotomised, before and after constriction of the inferior vena cava are shown in fig. 1. After the first operation albumin appeared in the urine, but disappeared a few days later. The vena cava was subsequently further constricted, and again protein appeared in the urine for a few days. So far as it is possible to judge from other experiments performed under anesthesia, and in which direct measure-