The intracellular lipin, mucoid, and glycogen of the vaginal epithelium of the guinea pig

Histological Changes in the Genital Tract of the Female Calf after the Administration of Diethylstilbestrol and Hexestrol

“…Changes of the type described in the vagina of calves have been reported extensively for several other animal species, such as rodents (LONG and EVANS, 1922;BIGGERS, 1953;BERN, ALFERT and BLAIR, 1957;DEANESLY, 1966;KIMURA, BASU and NANDI, 1967; LADINSKY, GRUCHOW and PECKHAM, 1968), pigs (DONE and HEARD, 1968;KURZ, NAIRN, NELSON, CHRISTENSEN and MIROCHA, 1969) and the cow (COLE, 1930). The changes reported after the administration of estrogens appear to be similar to those found in estrus (ALLEN, 1922;ALLEN and DOISY, 1923;ZUCKERMAN, 1940;TRIBBY, 1943;HUGGINS, JENSEN and STOCK CLEVE-LAND, 1954;BARKER and WALKER, 1966;THRASHER, CLARK and CLARKE, 1967). The estrogenic effect reported in the literature consists of a proliferation to squamous epithelium with or without keratinization, whereas the layer of mucous cells partly disappears, and partly changes into tall secretory cells.…”

Glycogen in the Epithelium of Mucous Membranes and Skin and Its Significance

“…As recognized by many authors, the break down of glycogen to glucose and then to lactic acid contributes to the m aintenance of the acid reaction of the vaginal content. According to some authors (Tribby [1943]) the appearance of glycogen in the vagina of anim als in the period of oestrus provides better conditions for the survival of sperm atozoa in the genital tract of the female.…”

“…Careful studies of Tribby [ 1943 ] on guinea pigs led him to som ewhat different conclusions regarding the tim e of appearance of glycogen in the vaginal epithelium and its functional significance. His findings show th at the m aximum glycogen accum ulation in the vaginal epithelium occurs in the stage preceding the onset of oestrus (prooestrus).…”

Vaginal mucins of indian gray mongoose, Herpestes edwardsii.

“…PAS positive mucus and glycogen of vaginal epithelium were reported in guinea pigs (31,3), albino mouse (20) and dog (33) ; neutral mucins in voles and guinea pigs (21) ; glycogen, acid and neutral mucins in rat (8) ; glycogen, neutral, sialo-and sulfomucins in bats (22) ; sulfated and non-sulfated acid mucins in mouse and rat (25) ; neutral mucins, acid sulfate and sialic acid in cow (10) ; sulfomucins and sialomucins in rat (2) and only sialic acid in mouse (4). In the present work, neutral, sialo-and sulfomucins were observed in the vagina of Herpestes.…”