“…The intestine is comprised of three tissue layers (Figure 01). The most external layer that wraps the intestinal tube is called muscularis externa, which is an innervated smooth muscle layer responsible for peristaltic activity in the intestine (MIXTER, 1915;Noah et al, 2011;Reed and Wickham, 2009). (Barker et al, 2012;Flier et al, 2009;Sancho et al, 2015).…”