Objective-This study compared an objective measurement of physical activity (PA) in individuals with anorexia nervosa (AN) at low-weight, weight-restored, and post-treatment time points, and also compared PA in AN with that of healthy controls (HC).Method-Sixty-one female inpatients with AN wore a novel accelerometer (the IDEEA) which measured PA at three time points: a) low-weight, b) weight-restored, and c) one month posthospital discharge. Twenty-four HCs wore the IDEEA at one time point.Results-Inpatients with AN became more physically active than they were at low-weight at weight restoration and following treatment discharge. Post-treatment patients with AN were more physically active than HCs during the day and less active at night, which was primarily accounted for by amount of time spent on feet, including standing and walking. Greater time spent on feet during the weight-restoration time point of inpatient treatment was associated with more rapid decrease in BMI over the 12 months following treatment discharge. Fidgeting did not differ between patients and controls, did not change with weight restoration, and did not predict posttreatment weight change.Discussion-Use of a novel accelerometer demonstrated greater PA in AN than in healthy controls. PA following weight restoration in AN, particularly time spent in standing postures, may contribute to weight loss in the year following hospitalization.
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Author ManuscriptAnorexia Nervosa (AN) is a serious psychiatric illness marked by self-starvation and overvaluation of shape and weight. There has been a longstanding interest in the role of physical activity (PA) in the etiology, maintenance, and prognosis of AN. A range of methods has been used to assess PA in AN, from subjective patient report of exercise frequency and drive to exercise, to objective devices such as accelerometers, which can quantify the frequency and duration of PA.Despite low weight, a significant subset of individuals with AN report that they engage in "excessive" or "compulsive" exercise (1), with one of the earliest clinical observations of a patient with AN by Dr. William Gull from 1868 noting that despite extremely low weight, the patient was "restless and active...it seemed hardly possible that a body so wasted could undergo the exercise which seemed agreeable"(2). This elevated level of exercise is associated with heightened psychopathology, such as depression, anxiety, and eating disorder symptomatology (3-6). Compulsive exercise during treatment is also negatively associated with improvements in eating disorder pathology by treatment discharge (3) and subjective report of compulsive exercise is associated with long-term lack of recovery from AN (7).Notwithstanding the longstanding clinical observation of heightened PA in AN, investigation of objective activity levels in patients with AN has yielded mixed results. While some studies have found that patients with AN are more active than healthy controls (8), oth...