The Interplay between 2-Arachidonoylglycerol and Anandamide Amidohydrolase in Neuropathy
Iddrisu Ibrahim,
Joseph Ayariga,
Junhuan Xu
et al.
Abstract:The endocannabinoid system (ECS) is a complex neuromodulatory network in the human body that have enormous impact in developing the central nervous system, as well as modulates various physiological processes. The ECS is made up of anandamide, 2-arachidonoylglycerol (2-AG), which are responsible for the synthesis and degradation of endocannabinoids, and enzymes such as FAAH and MAGL ensures the precise control over endocannabinoid levels. The ECS relies on CB1 receptors found in the central nervous system (CNS… Show more
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