The interactions between tetrapyridyl porphyrin and viologen units covalently linked to polymers

Bartczak, Adam; Namiki, Yuka; Qian, Dong−Jin; Miyake, Jun; Boguta, Andrzej; Goc, J.; Łukasiewicz, Jȩdrzej; Fra̧ckowiak, D.

doi:10.1016/s1010-6030(03)00190-4

Cited by 8 publications

(2 citation statements)

References 37 publications

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“…While there are early literature reports on the application of LIOAS and PA spectroscopy to porphyrins related to their fundamental photophysical characterization , the porphyrin, and related tetrapyrrole PAI‐based literature is relatively sparse considering the rich photochemistry for this class of chromophore. The earliest example of a tetrapyrrole study related to PAI, to the best of our knowledge, is a 2002 report by Stolik et al .…”

Section: Molecular Photoacoustic Contrast Agentsmentioning

confidence: 99%

Molecular Photoacoustic Contrast Agents: Design Principles & Applications

Borg

Rochford

2018

Photochem & Photobiology

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Photoacoustic imaging (PAI) is a rapidly growing field which offers high spatial resolution and high contrast for deep-tissue imaging in vivo. PAI is nonionizing and noninvasive and combines the optical resolution of fluorescence imaging with the spatial resolution of ultrasound imaging. In particular, the development of exogenous PA contrast agents has gained significant momentum of late with a vastly expanding complexity of dye materials under investigation ranging from small molecules to macromolecular proteins, polymeric and inorganic nanoparticles. The goal of this review is to survey the current state of the art in molecular photoacoustic contrast agents (MPACs) for applications in biomedical imaging. The fundamental design principles of MPACs are presented and a review of prior reports spanning from early-to-current literature is put forth.

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Section: Molecular Photoacoustic Contrast Agentsmentioning

confidence: 99%

Molecular Photoacoustic Contrast Agents: Design Principles & Applications

Borg

Rochford

2018

Photochem & Photobiology

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“…For the most of porphyrin‐functionized polymers, the porphyrin‐functionization is always conducted via the chemical reaction between the reactive groups of the matrix polymers and porphyrins, so that the porphyrin units are bound to the polymer matrix. Generally, in order to creating the chemical connection between matrix polymers and porphyrins, troublesome multi‐step polymer reactions are always needed for the chemical modification of the matrix polymers, and it is also needed to make porphyrins to have reactivity 19–23. Besides, various porphyrins need to be synthesized and separated firstly, and in the process, the synthesis and purification of single completely unsymmetrical porphyrins are often involved.…”

Section: Introductionmentioning

confidence: 99%

Realizing porphyrin‐functionalization of crosslinked polystyrene microspheres via two special polymer reactions

Gao

Yingjun

Lei

2011

Polymers for Advanced Techs

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A novel route to make crosslinked polystyrene (CPS) microspheres to be porphyrin-functionalized via two special polymer reactions, Kornblum reaction and Adler reaction, was designed and founded. The chloromethyl groups of chloromethylated crosslinked polystyrene (CMCPS) microspheres were first oxidized to aldehyde groups by dimethyl sulfoxide as oxidant via Kornblum oxidation reaction, obtaining aldehyde group-modified microspheres, ALCPS microspheres, in which, a great quantity of benzaldehyde groups suspend from the main chain, and the effects of the main factors including the reaction temperature, the addition of KI as catalyst and the used amount of NaHCO 3 as acid acceptor on the oxidation reaction were examined. Subsequently, the synchronic synthesizing and immobilizing of porphyrins on CPS microspheres were carried out via the Adler reaction between solid and liquid phases, in which, ALCPS microspheres, pyrrole and benzaldehyde or benzaldehyde analog in a solution were used as co-reactants, resulting in porphyrin-functionalized microspheres, and the influence of diverse factors including the acidity of the protonic acid catalyst, the substituent structure of benzaldehyde analog, and the polarity of the solvent as well as the swelling property of the solvent for CPS microspheres on the process of synchronously synthesizing and immobilizing porphyrins on CPS microspheres were investigated in depth. The experimental results indicate that via the designed route, the porphyrin-functionalization of CPS microspheres can successfully be realized. For the Kornblum oxidation reaction, under the optimal reaction conditions, the conversion of chloromethyl groups can reach 90%. For the Adler reaction between solid and liquid phases, the fitting protonic acid catalyst is lactic acid, appropriate solvent is a mixture of dimethyl sulfoxide and xylene, and using 4-chlorobenzaldehyde as a benzaldehyde analog reactant in the solution is in favor of the porphyrin-functionalization of CPS microspheres. Under these specific conditions, the immobilized amount of porphyrin can get up to 23.33 mmol/100 g.

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The novel polymeric systems for photodynamic therapy technique

Saboktakin¹,

Tabatabaee²

2014

International Journal of Biological Macromolecules

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The interactions between tetrapyridyl porphyrin and viologen units covalently linked to polymers

Cited by 8 publications

References 37 publications

Molecular Photoacoustic Contrast Agents: Design Principles & Applications

Molecular Photoacoustic Contrast Agents: Design Principles & Applications

Realizing porphyrin‐functionalization of crosslinked polystyrene microspheres via two special polymer reactions

The novel polymeric systems for photodynamic therapy technique

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