The inter‐rater and test‐retest reliability of skin thickness and skin elasticity measurements by the DermaLab Combo in healthy participants

Peperkamp, Kirsten; Verhulst, Arico C.; Tielemans, H.J.P.; Winters, Harm; Dalen, Demi van; Ulrich, Dietmar

doi:10.1111/srt.12718

Cited by 13 publications

(32 citation statements)

References 9 publications

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“…Recognizing that it may not be possible to use the values from one cheek to replace another, previous studies have included a rest period of 45 minutes between repeated measurements in order to avoid consequences of hysteresis. 24 Further, repeated measurements, up to three times, 25 would provide a mean score and potentially accommodate out of range or missing values. Future work should incorporate these methods to reduce missing data.…”

Section: Discussionmentioning

confidence: 99%

“…The test-re-rest reliability of skin elasticity measurements while avoiding cofounding has been described in a previous study. 24 Given this information, a potential solution would be to perform baseline measurements of cheek skin elasticity on both cheeks, such that any measurement out of range can be performed on the other cheek without hindering the statistical significance of the results. Recognizing that it may not be possible to use the values from one cheek to replace another, previous studies have included a rest period of 45 minutes between repeated measurements in order to avoid consequences of hysteresis.…”

Section: Discussionmentioning

confidence: 99%

“…129.9 ± 8.7 (23) 131.1 ± 8.2 (24) . Basophil Count (×10 9 /L) Screening 0.020 ± 0.041 (25) 0.012 ± 0.033 (25) .454 b…”

Section: Week 12mentioning

confidence: 99%

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A randomized, triple‐blind, placebo‐controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity

Evans¹,

Lewis²,

Zakaria³

et al. 2020

J of Cosmetic Dermatology

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Background: Collagen is the primary component in human skin. With age, there is loss of skin elasticity and collagen, resulting in wrinkle formation and reduction in skin appearance. Aims: The objective of this randomized, triple-blind, placebo-controlled study was to evaluate the safety and efficacy of a hydrolyzed marine collagen (Vinh Wellness Collagen, VWC) on aspects of skin health and quality in women between 45 and 60 years of age. Patients/Methods: Assessments of skin wrinkles, elasticity, and self-reported appearance were conducted using the VISIA skin analysis system, Cutometer ® , and Skin Quality Visual Analogue Scale. Outcomes were assessed at weeks 0 (baseline), 6, and 12. Results: After 12 weeks, participants supplemented with VWC had a significant 35% reduction in wrinkle score (P = .035) from baseline. Participants in the VWC group showed a 24% greater reduction in wrinkles on the right side of the face than those on placebo. A planned subgroup analysis based on age showed women 45-54 years had a significant 20% and 10% improvement in cheek skin elasticity from baseline to week 6 (P = .016) and 12 (P = .022), respectively. At week 12, participants in the VWC group reported greater percentage improvements in overall skin score (9%) and wrinkle (15%), elasticity (23%), hydration (14%), radiance (22%), and firmness (25%) scores vs placebo. Conclusion: Supplementation with VWC was found to be safe and well-tolerated. The results of this study support the use of fish-derived hydrolyzed collagen for the improvement of skin health in an aging population.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A randomized, triple‐blind, placebo‐controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity

Evans¹,

Lewis²,

Zakaria³

et al. 2020

J of Cosmetic Dermatology

View full text Add to dashboard Cite

show abstract

“…Additionally, the reference values of all reliable tests require age‐specific adjustments, as the photoaging process in women affects the skin function and ultrastructure 13 . In our study, we have used the multi‐parameter skin analysis system Dermalab Combo SkinLab, and reliability of which has been tested in different trials 18‐20 …”

Section: Introductionmentioning

confidence: 99%

Comparative analysis of effects induced by hyaluronic acid and its combined formula on skin functional parameters in second‐degree photoaging

Azaryan¹,

Khachikyan

Taha

et al. 2021

J of Cosmetic Dermatology

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Background and Aims The study aimed to compare the effectiveness of intradermal injections of modified hyaluronic acid (mHA) and combined injections of platelet‐rich plasma (PRP) and mHA (HA‐PRP) on clinical and functional parameters in women with second‐degree photoaging. Methods Seventy‐six healthy female participants diagnosed with second degree of skin photoaging were involved in two interventional study groups. The first group was treated with “bio‐reparative” method (mHA) and the second group with “combined HA‐PRP therapy”. Additionally, 20 practically healthy women, with the first degree of photoaging according to Glogau classification, constituted the control group. Parameters of facial skin were evaluated in all groups before and after the injections. The patients in both interventional groups were compared based on skin therapy outcomes, using corneometry, sebumetry, cutometry, transepidermal water loss (TEWL), and skin pH assessments. A post‐interventional analysis was conducted to evaluate the level of satisfaction in physicians and study participants in accordance with GAIS. Intragroup and between‐group analysis for the selected parameters was performed. Results Compared with the control group, the combined therapy group did not show significant difference in parameters (p > 0.05) and the scores were significantly improved compared to mHA group (p < 0.001). Control and HA‐PRP–treated groups were different only in sebumetry scores (SigDev = 2.1%). Significant difference was observed in the GAIS scores for patients between the interventional groups (p = 4.03297E−11 and 3.4093E−09, respectively). Conclusion Implementation of combined therapy is significantly effective compared to the mHA therapy alone. The higher efficacy is derived from significant recovery of functional parameters and GAIS survey results.

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“…evaluates skin elasticity and hardness, [10][11][12][13] ultrasound elastography uses Young's modulus to describe tissue stiffness, 5,[14][15][16][17][18][19] DermaLab/ DermaLab Combo define elastic properties, [20][21][22][23][24][25] SkinFibrometer measures skin induration 5,[26][27][28][29] and most commonly used Cutometer measures skin elastic and viscoelastic properties. 5,7,10,26,[30][31][32][33][34] Suction methods are one of the most widely used in basic and in applied skin research.…”

mentioning

confidence: 99%

Skin biomechanical and viscoelastic properties measured with MyotonPRO in different areas of human body

Rosicka¹,

Mierzejewska-Krzyzowska²,

Mrówczyński

2021

Skin Research and Technology

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Background: There is still a lack of clinically practical device, which allows to perform rapid and accurate examination of the skin condition. For this reason, suitability of the MyotonPRO for the assessment of skin biomechanical and viscoelastic parameters was evaluated in this study. The aim of the study was to establish the reference values of five parameters measured by MyotonPRO various locations of human skin. Materials and methods:Oscillation frequency, dynamic stiffness, logarithmic decrement, mechanical stress relaxation and creep were measured at three different skin locations (clavicula, volar forearm and shin), using L-shape short and medium arm probes in 32 young female volunteers. Mean values of obtained parameters recorded by both probes were compared among three skin locations while reliabilities of measurements were assessed. Additionally, relationships between all recorded parameters were examined Results: There were no statistically significant differences between the mean values of five measured parameters obtained with both probes in all investigated areas. However, statistically significant differences of mean values of almost all parameters measured among three places examined were found. Despite considerable differences in mean values of obtained parameters, there were visible strong correlations between some studied parameters in all three investigated areas of skin. Conclusion:It was demonstrated in all locations studied that the higher value of oscillation frequency corresponds to the higher value of dynamic stiffness, moreover such tissue recovers faster to its initial shape, and it was characterized by lower creep values.Such results indicate the existence of identical relationships between the same studied parameters in different areas of skin.

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The inter‐rater and test‐retest reliability of skin thickness and skin elasticity measurements by the DermaLab Combo in healthy participants

Cited by 13 publications

References 9 publications

A randomized, triple‐blind, placebo‐controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity

A randomized, triple‐blind, placebo‐controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity

Comparative analysis of effects induced by hyaluronic acid and its combined formula on skin functional parameters in second‐degree photoaging

Skin biomechanical and viscoelastic properties measured with MyotonPRO in different areas of human body

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