The intensive care of infants with hypoplastic left heart syndrome

Coronary anatomy in children with bicuspid aortic valves and associated congenital heart disease

“…Clinical consequence of this is unclear. In patients with HLHS, the arterial duct is the main source of systemic blood flow and provides retrograde filling to the coronary arteries 33. High take-off coronary arteries have been associated with acute angulation,16 potentially forming an impediment to this retrograde coronary flow.…”

Early hybrid approach and enteral feeding algorithm could reduce the incidence of necrotising enterocolitis in neonates with ductus-dependent systemic circulation

“…The altered systemic blood flow due to impaired right ventricular contractility, tricuspid valve regurgitation, and the tenuous balance between pulmonary and systemic blood flows may explain the higher incidence of necrotising enterocolitis in neonates with hypoplastic left heart syndrome compared with those with other forms of CHD (7.6 versus 2.1%). 14 We believe that the systemic vasodilator therapy, [16][17][18] incorporated in our perioperative management protocol, could represent a protective factor for necrotising enterocolitis. The use of milrinone in neonates with CHD increases cardiac output with a concurrent effect on splanchnic and cerebral blood flow during the short perioperative time.…”

Transplante cardíaco pediátrico em vigência de choque cardiogênico refratário: análise crítica da viabilidade, aplicabilidade e resultados

“…Extracorporeal membrane oxygenation has increasingly gained popularity in the treatment of this specific group of patients, with promising results that have brought hospital mortality down to 11% 2,9,10,17,18 . Additionally, long-term results also support the use of this type of device 17,19,20 .…”