The Intelligence of Hydrocephalic Children

Dennis, Maureen; Fitz, Charles R.; Netley, C.; Sugar, Judith A.; Harwood-Nash, Derek C.; Hendrick, E B; Hoffman, H J; Humphreys, Robin P.

doi:10.1001/archneur.1981.00510100035004

Cited by 215 publications

(105 citation statements)

References 51 publications

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“…Some authors have reported that children who develop hydrocephalus in the prenatal or postnatal period have cognitive impairment [5, 16, 17, 18, 19]. Most studies concerned lower non-verbal ability (PIQ) compared with verbal ability (VIQ) in intelligence tests.…”

Section: Discussionmentioning

confidence: 99%

MRI Morphometric Study and Correlation with Cognitive Functions in Young Adults Shunted for Congenital Hydrocephalus Related to Spina bifida

Hommet

Cottier²,

Billard³

et al. 2002

Eur Neurol

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We studied the morphometric MRI findings and their correlation with cognitive functions in a population of 10 young adults shunted for congenital hydrocephalus related to spina bifida. Morphometric MRI analysis included measurement of the ventricular dilatation index, frontal and occipital parenchymal thickness and the size of the corpus callosum. The neuropsychological status was evaluated, notably to look for a discrepancy between verbal and performance skills, a finding which has previously been described in hydrocephalic children. We also investigated whether there was a correlation between cognitive function and cerebral morphometric indexes. In each case, MRI demonstrated the structural changes associated with the Chiari II malformation. The size of the lateral ventricles varied, ranging from important dilatation to small ventricles. Six patients had only partial development of the corpus callosum. All patients had a normal global IQ. In our population of young adults, we did not observe any discrepancy between verbal and visuospatial performances as has been described in children with hydrocephalus. We found no relationship between cognitive function and ventricle dilatation or parenchymal thickness or between the size of the corpus callosum and callosal transfer.

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Section: Discussionmentioning

confidence: 99%

MRI Morphometric Study and Correlation with Cognitive Functions in Young Adults Shunted for Congenital Hydrocephalus Related to Spina bifida

Hommet

Cottier²,

Billard³

et al. 2002

Eur Neurol

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show abstract

“…These poor results were related to the severity of the hydrocephalus. This risk factor has also been reported in children with idiopathic hydrocephalus or hydrocephalus secondary to aqueductal stenosis [13, 28, 29]. However, the association of complex cardiac anomalies added an additional risk for mortality.…”

Section: Discussionmentioning

confidence: 55%

The Prognosis of Children with Hydrocephalus and Congenital Heart Disease

Crawford

Olivero

2000

Pediatr Neurosurg

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The association of congenital hydrocephalus and heart disease in children is infrequent, but may present considerable dilemmas in management. This report describes the treatment and prognosis of 11 children with both clinical problems. There were 5 males and 6 females. Hydrocephalus occurred following aqueductal stenosis in 5 children and the Dandy-Walker malformation in 3. Three children were diagnosed with idiopathic hydrocephalus. Ten children underwent cerebrospinal fluid diversion procedures for control of hydrocephalus. Five children received pharmacological therapy for cardiac disease; 4 children required surgical correction. Two children died from medical conditions; 2 families declined treatment. Follow-up from 2 to 7 years in the remaining 7 children demonstrated moderate or severe neurodevelopmental disability in 5. One child at 2 years of age showed borderline developmental disability while 1 child is developing normally at 10 years of age. Overall the occurrence of symptomatic hydrocephalus and heart disease in the perinatal period resulted in mortality or neurodevelopmental disability in 9/11 children.

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“…Several studies have attempted to measure quality of life and performance of children surviving brain tumors, even though the quality of life measures lack standardization [12, 13, 14, 15, 16]. Ellenberg et al [10]conducted a prospective study of intellectual outcome in 73 children with brain tumors consecutively admitted to the hospital over a period of 3 years.…”

Section: Etiological Factors and Pathologic Findingsmentioning

confidence: 99%

Late Effects of Therapy of Thalamic and Hypothalamic Tumors in Childhood: Vascular, Neurobehavioral and Neoplastic

Siffert

Allen²

2000

Pediatr Neurosurg

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The late effects in children with hypothalamic and thalamic tumors relate to the effects of the tumor on the surrounding brain, the effects of surgery, radiotherapy (RT) and, to a lesser extent, chemotherapy. The clinical manifestations of late effects include endocrinologic dysfunction, neurocognitive sequelae, behavioral problems and second neoplasia. The prevention of late effects is an integral part of current treatment strategies. Early diagnosis, a rational use of surgery, and deferral of RT are the mainstays of the modern treatment in these patients. The improvement of RT techniques and the use of radioprotective compounds may further help spare normal brain tissue. A better understanding of chemotherapy use and the development of newer agents may increase efficacy, reduce side effects and allow deferral of RT in a greater percentage of patients. Finally, an aggressive management of endocrinological problems, physical and cognitive rehabilitation as well as psychological and school support help provide these children with maximal function within their potential.

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The Intelligence of Hydrocephalic Children

Cited by 215 publications

References 51 publications

MRI Morphometric Study and Correlation with Cognitive Functions in Young Adults Shunted for Congenital Hydrocephalus Related to Spina bifida

MRI Morphometric Study and Correlation with Cognitive Functions in Young Adults Shunted for Congenital Hydrocephalus Related to Spina bifida

The Prognosis of Children with Hydrocephalus and Congenital Heart Disease

Late Effects of Therapy of Thalamic and Hypothalamic Tumors in Childhood: Vascular, Neurobehavioral and Neoplastic

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