The inpatient burden of pyoderma gangrenosum and associated comorbidities in children in the United States

Narla, Shanthi; Silverberg, Jonathan I.

doi:10.1007/s00403-021-02189-z

Arch Dermatol Res

2021

DOI: 10.1007/s00403-021-02189-z

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The inpatient burden of pyoderma gangrenosum and associated comorbidities in children in the United States

Shanthi Narla

Jonathan I. Silverberg

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2022

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Cited by 1 publication

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Neutrophilic Dermatoses: a Clinical Update

Weiss

Leung

et al. 2022

Curr Derm Rep

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Purpose of Review Neutrophilic dermatoses are defined by the presence of a sterile neutrophilic infiltrate on histopathology. This review focuses on the pathogenesis, epidemiology, clinicopathological features, diagnosis, and management of four disorders: Sweet syndrome, pyoderma gangrenosum, Behçet syndrome, and neutrophilic eccrine hidradenitis.Recent Findings Recent studies have provided insight into the complex pathogenesis of neutrophilic dermatoses. Evidence supports an intricate interplay of abnormal neutrophil function and inflammasome activation, malignant transformation into dermal infiltrating neutrophils, and genetic predisposition. Summary Neutrophilic dermatoses have diverse cutaneous and extracutaneous manifestations and may be associated with significant morbidity and mortality. Common underlying associations include infectious, inflammatory, and neoplastic disorders, as well as drug reactions. Emerging diagnostic and therapeutic frameworks identify an expanding role for biologic and targeted anti-inflammatory therapies. KeywordsAcute febrile neutrophilic dermatosis • Behçet disease • Neutrophilic dermatosis • Neutrophilic eccrine hidradenitis • Pyoderma gangrenosum • Sweet syndrome This article is part of the Topical Collection on Hospital-Based Dermatology

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Neutrophilic Dermatoses: a Clinical Update

Weiss

Leung

et al. 2022

Curr Derm Rep

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The inpatient burden of pyoderma gangrenosum and associated comorbidities in children in the United States

Cited by 1 publication

References 5 publications

Neutrophilic Dermatoses: a Clinical Update

Neutrophilic Dermatoses: a Clinical Update

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