The Inhibitory Effect of Pyridoxamine Upon the Development of Resistance of Mycobacterium Tuberculosis Var. Avium to Streptomycin

Abstract

Streptomycin remains to be considered as one of the most valuable chemo therapeutic agent for the treatment of tuberculosis. However, the problem of the rapid and strong development of resistance to streptomycin is faced by clinicians at all times in the treatment of the disease. If it were possible in some way to completely prevent the appearance of resistant strains either in vivo or in vitro, the contribution to chemotherapy would be extremely