The influences of depression and loneliness on A1C among middle-aged and older adults with diabetes

Huang, Ya-Ching; Cho, Emma; Kuo, Hsuan-Ju; García, Alexandra

doi:10.1080/13548506.2022.2124287

Cited by 8 publications

(8 citation statements)

References 24 publications

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“…relationship between 'felt lonely' and 'couldn't get going' was significantly stronger for people with diabetes than for those without. Perceived loneliness has been shown to be significantly predictive of higher HbA1c in people with self-reported diabetes, after controlling for demographics, depression, and number of chronic illnesses (Huang et al, 2022). Diabetes self-management behaviours appear to be impacted by levels of social support (Koetsenruijter et al, 2016, Strom & Egede 2012.…”

Section: Discussionmentioning

confidence: 99%

A network analysis of depressive symptoms in adults with and without diabetes: findings from the Irish longitudinal study on ageing

Byrne,

McInerney,

Deschênes

2024

Ir. j. psychol. Med.

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Objectives: This study aimed to estimate networks of depressive symptoms among Irish adults with and without diabetes at two time points and compare between the two groups at each time point using data from the Irish Longitudinal Study on Ageing (TILDA). Methods: Participants were from Wave 1 (2009–2011) and Wave 4 (2016) of TILDA, with n = 639 participants with diabetes and n = 7,837 without diabetes at Wave 1, and n = 1,151 with diabetes and n = 4,531 without diabetes at Wave 4. Depressive symptoms were measured using the 8 items of the Center for Epidemiologic Studies Depression Scale. Network psychometric analysis was used to examine symptom centrality, symptom-level associations, and network comparisons at each time point. Results: Stable, strongly connected networks emerged for people with and without diabetes at both time points. The symptoms of feeling depressed, feeling like everything’s an effort, not enjoying life, feeling sad, and couldn’t get going were the most central nodes in all networks, which did not differ between people with and without diabetes. However, for people with diabetes, the network was more densely connected at Wave 4, when the sample was predominately people with newly diagnosed diabetes. Furthermore, the relationship between ‘felt lonely’ and ‘couldn’t get going’ and between ‘not enjoying life’ and ’sad’ was significantly stronger for people with diabetes than for those without. Conclusions: This study provides a more detailed understanding of the structure of depressive symptoms at two time points in older Irish adults with and without type 1 or type 2 diabetes.

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Section: Discussionmentioning

confidence: 99%

A network analysis of depressive symptoms in adults with and without diabetes: findings from the Irish longitudinal study on ageing

Byrne,

McInerney,

Deschênes

2024

Ir. j. psychol. Med.

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“…Finally, this study has provided a novel nding about the relationship between T2DM and loneliness in the population with high SES and healthy life. We utilized the fully validated questionnaire, the entire UCLA Loneliness scale, which solved the limitations of the previous US study that used an unvalidated questionnaire 7 . In conclusion, the association between loneliness and HbA1c has not been observed in the high SES population of this study.…”

Section: Discussionmentioning

confidence: 99%

Impact of loneliness on blood glucose: a cross-sectional survey among Japanese

Quyen,

Nakamura,

Watanabe

et al. 2023

Preprint

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Although the correlation between loneliness and both the development and management of diabetes has been gradually uncovered, the finding was inclusive. Furthermore, this aspect has yet to be researched in the Japanese populace. Therefore, this cross-sectional study analyzed data from the Kanagawa prospective “ME-BYO” Cohort Study (ME-BYO cohort) to investigate the correlation between loneliness and HbA1c. A total of 666 participants were included in the analysis, with a mean age of 54.1 years and a mean BMI of 23 kg/m2. Half of the participants had obtained an education level beyond high school. The mean household income and physical activity level were reported as 6.83 million Japanese yen and 12.3 METs-h/day, respectively. Linear regression analysis determined no significant association between the loneliness scale and HbA1c (p = 0.512). The lack of association persisted even after adjusting for age, sex, and BMI. Thus, the study found no link between loneliness and HbA1c in the high SES population. This finding contradicts prior results and may be attributed to the impact of population characteristics, SES status, or genetic backgrounds. Trial registration: not applicable

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“…In a longitudinal study of 4112 diabetes‐free participants, loneliness was an independent risk factor for type 2 diabetes 92 . In another study, loneliness predicted high haemoglobin A1c levels in diabetic patients 93 …”

Section: The Impact Of Social Isolation and Loneliness On Chronic Dis...mentioning

confidence: 98%

“…Hackett et al 92 • Loneliness is a potential risk factor for type 2 diabetes • Among the 264 (6.42%) individuals who developed type 2 diabetes over the follow-up, loneliness is significantly associated with the development of diabetes (HR 1.46, 95% CI 1.15-1.84, p = .002) independent of age, sex, ethnic origin, tobacco consumption, physical activity, wealth, alcohol use, hypertension, body mass index, HbA1c and cardiovascular disease • In addition, a significant relationship between loneliness and type 2 diabetes onset exists (HR 1.41, 95% CI 1.04-1.90, p = .027) independent of social isolation, symptoms of depression, living alone and with social isolation and living alone not having a significant effect on the onset of type 2 diabetes Huang et al 93 • Loneliness is shown as a significant predictor of elevated HbA1c levels in diabetic patients • Individuals with increased levels of loneliness have a significantly elevated risk of having HbA1c >7 (OR 1.18, p < .05) after adjusting for depression and all other variables and loneliness is reported to have a larger effect on HbA1c than depression in diabetic patients Zhou et al 94 • A significant association exits between social isolation and the risk of rapid fall in the eGFR as well as CKD onset 95 • Individuals with CKD stages 3b-5 have significantly decreased social contact and social participation (p < .05).…”

Section: Name/study Outcomesmentioning

confidence: 98%

Social isolation and loneliness: Undervalued risk factors for disease states and mortality

Kanbay

Tanrıöver

Çöpür

et al. 2023

Eur J Clin Investigation

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Social isolation and loneliness are two common but undervalued conditions associated with a poor quality of life, decreased overall health and mortality. In this review, we aim to discuss the health consequences of social isolation and loneliness. We first provide the potential causes of these two conditions. Then, we explain the pathophysiological processes underlying the effects of social isolation and loneliness in disease states. Afterwards, we explain the important associations between these conditions and different non‐communicable diseases, as well as the impact of social isolation and loneliness on health‐related behaviours. Finally, we discuss the current and novel potential management strategies for these conditions. Healthcare professionals who attend to socially isolated and/or lonely patients should be fully competent in these conditions and assess their patients thoroughly to detect and properly understand the effects of isolation and loneliness. Patients should be offered education and treatment alternatives through shared decision‐making. Future studies are needed to understand the underlying mechanisms better and to improve the treatment strategies for both social isolation and loneliness.

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The influences of depression and loneliness on A1C among middle-aged and older adults with diabetes

Cited by 8 publications

References 24 publications

A network analysis of depressive symptoms in adults with and without diabetes: findings from the Irish longitudinal study on ageing

A network analysis of depressive symptoms in adults with and without diabetes: findings from the Irish longitudinal study on ageing

Impact of loneliness on blood glucose: a cross-sectional survey among Japanese

Social isolation and loneliness: Undervalued risk factors for disease states and mortality

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