Shape memory alloys with two different weight percentages of CuAlBe were irradiated with a 40 kGy constant gamma radiation dose, and the resulting thermal and structural changes in the alloys were examined. Changes in enthalpy and in the transformation temperature of the alloys were determined by differential scanning calorimetry (DSC), and thermodynamic parameters of alloy samples were calculated. Microstructural changes were determined by X-ray analysis. Microstructural changes were verified by metallographic observations, and microhardness measurements were taken. The study investigated to what extent the physical parameters of CuAlBe shape memory alloys changed depending on the alloying elements when subjected to a constant irradiation dose.