The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics

Said, SA; A, Aribarg; Virutamsen, P; Chutivongse, Supawat; Koetsawang, Suporn; Meherjee, P; Kumar, T.M.A. Senthil; Cuadros, Alvaro; Shearman, RP; Conway, Ann J.; An, Gupta; Dhall, G I; Majumdar, S.; Dt, Baird; Comhaire, Frank; Padron, RS; Más, Jorge; Gonzales, MA; Ladipo, DA

doi:10.1016/0020-7292(93)90883-x

Cited by 63 publications

(20 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A varicocele incidence of 25.6% was observed in a large observational study involving more than 9,000 men [32]. In this study, men with varicocele were also shown to have lower total sperm count and testosterone levels, as well as reduced testicular size on the same side of varicose vessels compared with those without varicocele.…”

Section: Varicocele and Infertility: A Controversial Issuesupporting

confidence: 50%

A Critical Appraisal on the Role of Varicocele in Male Infertility

Miyaoka

Esteves

2012

Advances in Urology

View full text Add to dashboard Cite

Varicocele is a major cause of male infertility, as it may impair spermatogenesis through several distinct physiopathological mechanisms. With the recent advances in biomolecular techniques and the development of novel sperm functional tests, it has been possible to better understand the mechanisms involved in testicular damage provoked by varicocele and, therefore, propose optimized ways to prevent and/or reverse them. Up to now, there is still controversy involving the true benefit of varicocele repair in subfertile men as well as in certain specific situations such as concomitant contralateral subclinical varicocele or associated nonobstructive azoospermia. Also, with the continued development of assisted reproductive technology new issues and questions are emerging regarding the role of varicocelectomy in this context. This paper reviews the most recent data available on the pathogenesis, diagnosis, and management of varicocele with regard to male infertility.

show abstract

Section: Varicocele and Infertility: A Controversial Issuesupporting

confidence: 50%

A Critical Appraisal on the Role of Varicocele in Male Infertility

Miyaoka

Esteves

2012

Advances in Urology

View full text Add to dashboard Cite

show abstract

“…The major concern for patients with a varicocele is infertility; with a varicocele present in 25-69 % of adults evaluated for infertility [4,5]. In contrast, 35 % of adults with primary infertility and 85 % with secondary infertility are found to have a varicocele [6].…”

Section: Introductionmentioning

confidence: 93%

The dilemma of adolescent varicocele

Garcia-Roig

Kirsch

2015

Pediatr Surg Int

View full text Add to dashboard Cite

Adolescent varicocele is associated with ipsilateral testicular hypotrophy and the concern for future infertility. A testicular size discrepancy greater than 15-20 % between left and right testicle is an indication for treatment to allow catch-up growth in the hope of preventing a future decline in fertility. Some authors advocate for a period of watchful waiting, as normal testicular growth may occur asymmetrically. We review the current literature to highlight some controversies and challenges in management.

show abstract

“…It is widely reported that varicoceles are usually larger and more common on the left side of the patients, and bilateral lesions are present in up to 50% of the patients (Abdulmaaboud et al, 1998). A lot of data suggested that varicoceles may result in reduced testicular volume, spermatogenesis disorder and a decline in Leydig cell function if left untreated (Chehval & Purcell, 1992;Kaneko, Sasaki, Yanai, Umemoto, & Kohri, 2007;Said et al, 1992). Some aetiologic and genetic factors are established to contribute to varicocele risk including venous insufficiency and single-nucleotide polymorphisms.…”

Section: Introductionmentioning

confidence: 99%

Lower body mass index and higher height are correlated with increased varicocele risk

Song

Liang

et al. 2019

Andrologia

View full text Add to dashboard Cite

To evaluate the anthropometric indexes in subjects with varicocele compared to controls and the incidence of varicocele in different body mass index (BMI) groups for the purpose of exploring the association between varicocele and anthropometric indexes. A comprehensive literature search was conducted by using PubMed, MEDLINE, EMBASE databases and Cochrane Library up to February 2019. A systematic review and meta-analysis was conducted by STATA, and Newcastle-Ottawa Scale was utilised for assessing risk of bias. Ultimately, 13 articles containing seven case-control studies and six cross-sectional studies with 1,385,630 subjects were involved in our study.Pooled results demonstrated that varicocele patients had a lower BMI (WMD = −0.77, 95% CI = −1.03 to −0.51) and a higher height than nonvaricocele participants, espe-How to cite this article:

show abstract

The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics

Cited by 63 publications

References 18 publications

A Critical Appraisal on the Role of Varicocele in Male Infertility

A Critical Appraisal on the Role of Varicocele in Male Infertility

The dilemma of adolescent varicocele

Lower body mass index and higher height are correlated with increased varicocele risk

Contact Info

Product

Resources

About