2015
DOI: 10.1515/labmed-2015-0060
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The influence of the trace element zinc on the immune system

Abstract: Clinical and experimental examinations showed a close relationship between zinc as an essential trace element and the immune system. Thus, cellular and humoral components from both the innate and the adaptive immune system are affected by zinc. Human zinc deficiencies are frequently connected with disturbed immune functions. Controlled zinc substitution results in a normalization of zinc serum levels, zinc homeostasis, and the immunological parameters. As shown in in vitro experiments, low zinc concentrations … Show more

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Cited by 4 publications
(2 citation statements)
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References 84 publications
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“…The essential trace element Zn is crucial for many physiological processes in humans, and it is one of the most frequently studied factors in nutrition and health. It plays elementary roles as a regulator or coenzyme of more than 300 enzymes [ 29 ]. It is also a component of transcription factors and is involved in the synthesis of DNA and RNA, as well as proteins.…”
Section: Zincmentioning
confidence: 99%
“…The essential trace element Zn is crucial for many physiological processes in humans, and it is one of the most frequently studied factors in nutrition and health. It plays elementary roles as a regulator or coenzyme of more than 300 enzymes [ 29 ]. It is also a component of transcription factors and is involved in the synthesis of DNA and RNA, as well as proteins.…”
Section: Zincmentioning
confidence: 99%
“…Zinc is a trace element that is vital for the immune system, sensory functions and metabolism as well as skin regeneration and protection [66,67]. Moreover, zinc ions, zinc oxides or zinc salts, such as zinc acetate, zinc chloride or zinc sulfate, are also used as antimicrobial finishes [60].…”
Section: Zincmentioning
confidence: 99%