Abstract. Simulated observations of total electron cornera (TEC) along ray paths from Global Positiomng System (GPS) satellites have been used to validate the estimation of TEC using GPS measuremeres. The Sheffield Umversity plasmasphere ionosphere model (SUPIM) has been used to create electron densities that were integrated along ray paths from actual configurations of the GPS constellation. The resultant slant electron contents were then used as inputs to validate the self-calibration of pseudo-range errors (SCORE) process for the deternfination of TEC from GPS observations. It is shown that if the plasma resides only in the ionosphere below 1100 km, then the SCORE procedure determines the TEC to a high degree of accuracy. When the contribution of the electrons in the protonosphere above 1100 km is included, the analysis results in TEC estimates that are high by some 2 TEC umts (TECU) for conditions appropriate to European nfidlatimdes at solar nfimmum However, if a restriction is placed in the analysis on use of observations equatorward of the station, then allowance can be made for the effect of the proionosphere. It is shown that with appropriate selection of the boundary for the observations, TEC can be estimated by SCORE to better than 1 TECU for the conditions of the simulation. Sample results are included from actual experimemal observations using GPS to demonstrate the effect of compensation for the protonosphenc plasma.