The influence of the menstrual cycle and pregnancy on atopic dermatitis

Kemmett, D.; Tidman, Michael J.

doi:10.1111/j.1365-2133.1991.tb06041.x

Cited by 104 publications

(62 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Cho et al, in a similar interview-based study in Korea found symptoms improvement in 4% while 61% experienced deteriorations [36]. Kemmett et al, documented deteriorations in 52%, improvement in 24% and stable disease in 24% [37]. Similar deterioration in the presence of premenstrual syndrome (PMS) was noted in 46% of women menstruating suggesting an existing relationship between pregnancy hormones and fluctuation of eczema in pregnancy [36,37].…”

Section: Discussionmentioning

confidence: 94%

“…Kemmett et al, documented deteriorations in 52%, improvement in 24% and stable disease in 24% [37]. Similar deterioration in the presence of premenstrual syndrome (PMS) was noted in 46% of women menstruating suggesting an existing relationship between pregnancy hormones and fluctuation of eczema in pregnancy [36,37]. However, the fact that psychological symptoms of PMS could increase awareness of cutaneous symptoms and failure of hormone replacement treatment suggest further studies are needed for better understanding of the role hormones.…”

Section: Discussionmentioning

confidence: 95%

See 1 more Smart Citation

The Prevalence, Risk Factors and Changes in Symptoms of Self Reported Asthma, Rhinitis and Eczema Among Pregnant Women in Ogbomoso, Nigeria

Adeyemi

Akinboro

Adebayo

et al. 2015

JCDR

View full text Add to dashboard Cite

Background: Allergic disorders have become a major public health concern worldwide. No Nigerian study has examined the epidemiology of allergic diseases among women. Aim:To document the prevalence, risk factors and the changes in the symptoms of allergic disorders during pregnancy. Settings and Design:Cross-sectional study conducted at the booking and antenatal clinics of LAUTECH Teaching Hospital and Millennium Development Goals (MDG) Clinic of the Comprehensive Health Center, Oja Igbo, Ogbomoso, Nigeria. Materials and Methods:Study enrolled 432 women from two public hospitals. Sociodemographic and clinical history were obtained and allergic disorders were diagnosed using ISAAC questionnaires.

show abstract

Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 95%

The Prevalence, Risk Factors and Changes in Symptoms of Self Reported Asthma, Rhinitis and Eczema Among Pregnant Women in Ogbomoso, Nigeria

Adeyemi

Akinboro

Adebayo

et al. 2015

JCDR

View full text Add to dashboard Cite

show abstract

“…Atopic dermatitis is more likely to deteriorate than to remit in pregnancy. 23 In some countries, especially Sweden and Chile-Bolivia, ICP patients constitute a fairly large patient group. We suggest that pregnant women with pruritus should be surveilled with repeated determinations of serum bile acids.…”

Section: Discussionmentioning

confidence: 99%

Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates

2004

View full text Add to dashboard Cite

Intrahepatic cholestasis of pregnancy (ICP), characterized by pruritus in the second half of pregnancy, entails an increased risk to the fetus. This study was designed to determine the incidence and fetal complication rates in ICP, and to define groups at increased risk. In an prospective cohort study conducted between February 1, 1999, and January 31, 2002, all 45,485 pregnancies in a defined region of Sweden (Västra Götaland) were screened for ICP, defined as otherwise unexplained pruritus of pregnancy in combination with fasting serum bile acid levels >10 mol/L. Pruritus was reported by 937 (2.1%) women, and ICP was diagnosed in 693 (1.5%). Simple logistic regression analyses showed that the probability of fetal complications (spontaneous preterm deliveries, asphyxial events, and meconium staining of amniotic fluid, placenta, and membranes) increased by 1%-2% per additional mol/L of serum bile acids. Complementary analyses showed that fetal complications did not arise until bile acid levels were >40 mol/L. Gallstone disease and a family history of ICP were significantly (P < .001) more prevalent in the group of ICP patients with higher bile acid levels. In conclusion, we found an incidence of ICP in our population of 1.5%. From complication rates recorded prospectively, we could define a mild (81%) and a severe (19%) form of ICP, the latter with bile acid levels >40 mol/L. No increase in fetal risk was detected in ICP patients with bile acid levels < 40 mol/L, and we propose that these women be managed expectantly, which would significantly reduce the costs of medical care. I ntrahepatic cholestasis of pregnancy (ICP) is a condition characterized by pruritus in the second half of pregnancy. It persists until delivery, after which it ceases promptly. A genetic background is suggested by family clustering and demographic variations, with the highest incidences reported from Chile-Bolivia (6%-27%) and Sweden (1-1.5%). 1 ICP is associated with an increased risk of preterm delivery in 19%-60%, 2-5 intrapartum fetal distress in 22%-41%, and intrauterine fetal death (IUFD) in 0.75%-1.6% of the affected pregnancies. [3][4][5][6] The diagnostic criteria for ICP have varied over time in different reports, making complication rates difficult to compare. When, in addition to pruritus, clinical jaundice was used to define ICP, higher fetal complication rates were reported than when diagnosis was based only on elevated bile acid and transaminase levels. 2,3,6 -8 The Swedish ICP incidence figure is taken from a study using only pruritus in pregnancy as the inclusion criterion, and that study did not report increased fetal risk associated with ICP. 9 Nowadays, elevation of serum bile acids is considered to be the most appropriate laboratory parameter for diagnosis of the condition. 8,10 -12 It is reasonable to believe that ICP constitutes a continuum, ranging from light to severe forms, but there has been an absence of algorithms to identify pregnancies entailing increased fetal risk. The aims of this prospective cohort stu...

show abstract

“…Pregnancy may also aggravate the symptoms in some patients, while in others an improvement may be seen. These observations strongly suggest that hormonal changes also have an influence on atopic eczema (38).…”

Section: Diagnosis and Avoidance Of Environmental Provocation Factorsmentioning

confidence: 73%

The therapeutic concept of “patient management” in atopic eczema

Ring

Brockow

Abeck

1996

Allergy

View full text Add to dashboard Cite

The influence of the menstrual cycle and pregnancy on atopic dermatitis

Cited by 104 publications

References 15 publications

The Prevalence, Risk Factors and Changes in Symptoms of Self Reported Asthma, Rhinitis and Eczema Among Pregnant Women in Ogbomoso, Nigeria

The Prevalence, Risk Factors and Changes in Symptoms of Self Reported Asthma, Rhinitis and Eczema Among Pregnant Women in Ogbomoso, Nigeria

Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates

The therapeutic concept of “patient management” in atopic eczema

Contact Info

Product

Resources

About