This paper was to explore the effect of spouse support and cognitive strategy for emotional regulation on retirement anxiety of middle aged men. The survey was carried out with middle aged employed men worked in 5 major cities. 313 copies of questionnaires were used in the survey except the ones insufficient respond. The data was analyzed by descriptive statistics, t-test, ANOVA, pearson correlation and Multiple Regression. As a result, Main results of this study could be presented as follows. Spouse support was the significant predictor to explain retirement anxiety of middle aged men, but cognitive strategy for emotional regulation didn't have the effectiveness to retirement anxiety of middle aged men. In conclusion, to alleviate retirement anxiety of middle aged men, in conjugal relations spouse support need to be strengthened.