The influence of the blood pressure on the venous cerebral flow measured by magnetic susceptibility (SWI) technique

Abstract

<div align="justify"> Susceptibility Weighted Image (SWI) is a Magnetic Resonance Imaging (MRI) technique that combines high spatial resolution and sensitivity to magnetic susceptibility differences between tissues, it is extremely sensitive to venous blood due to its iron content of deoxyhemoglobin. The aim of this study was to evaluate the differences in the cerebral venous vasculature produced by the value’s variation of blood pressure. 20 subjects (10 hypertensive and 10 normotensive patients) underwent a MRI system with field strength of 1.5 T using a synergy head coil (7 channels). The obtained sequences were T1w, T2w-FLAIR, T2* and SWI. The value of Contrast-to-Noise Ratio (CNR) was assessed in MinIP (Minimum Intensity Projection) and Magnitude images, through drawing free hand ROIs in venous structures: Superior Sagittal Sinus (SSS) Internal Cerebral Vein (ICV) and Sinus Confluence (SC). The obtained values were presented in descriptive statistics-quartiles and extremes diagrams. The results were compared between groups. CNR shown higher values for normotensive group in MinIP (108.89 ± 6.907) to ICV; (238.73 ± 18.556) to SC and (239.384 ± 52.303) to SSS. These values are bigger than images from Hypertensive group about 46 au in average. Comparing the results of Magnitude and MinIP images, there were obtained lower CNR values for the hypertensive group. There were differences in the CNR values between both groups, being these values more expressive in the large vessels-SSS and SC. The SWI is a potential technique to evaluate and characterize the blood pressure variation in the studied vessels adding a physiological perspective to MRI and giving a new approach to the radiological vascular studies. </div

The effects of stent porosity on the endovascular treatment of intracranial aneurysms located near a bifurcation

“…Conse- man cardiovascular system, e.g. lumped parameter models [56] and magnetic resonance imaging techniques [57].…”