The influence of textile vascular prosthesis crimping on graft longitudinal elasticity and flexibility

Hajjaji, R.; Abdessalem, Saber Ben; Ganghoffer, J.F.

doi:10.1016/j.jmbbm.2012.06.017

Cited by 9 publications

(6 citation statements)

References 8 publications

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“…The continuous stretch subsequently produces structural fatigue of the arterial wall at the anastomosis [ 5 ]. A significant amount of research has been done on optimising construction and handling properties of woven grafts [ 34 , 35 , 36 , 37 , 38 , 39 ] but radial compliance/elasticity is still an unresolved issue [ 27 , 40 ] and has a direct influence on long term patency of these grafts ( Table 2 ).…”

Section: Textile Structures As Vascular Implantsmentioning

confidence: 99%

Medical Textiles as Vascular Implants and Their Success to Mimic Natural Arteries

Singh

Wong

Wang

2015

JFB

149

101

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Vascular implants belong to a specialised class of medical textiles. The basic purpose of a vascular implant (graft and stent) is to act as an artificial conduit or substitute for a diseased artery. However, the long-term healing function depends on its ability to mimic the mechanical and biological behaviour of the artery. This requires a thorough understanding of the structure and function of an artery, which can then be translated into a synthetic structure based on the capabilities of the manufacturing method utilised. Common textile manufacturing techniques, such as weaving, knitting, braiding, and electrospinning, are frequently used to design vascular implants for research and commercial purposes for the past decades. However, the ability to match attributes of a vascular substitute to those of a native artery still remains a challenge. The synthetic implants have been found to cause disturbance in biological, biomechanical, and hemodynamic parameters at the implant site, which has been widely attributed to their structural design. In this work, we reviewed the design aspect of textile vascular implants and compared them to the structure of a natural artery as a basis for assessing the level of success as an implant. The outcome of this work is expected to encourage future design strategies for developing improved long lasting vascular implants.

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Section: Textile Structures As Vascular Implantsmentioning

confidence: 99%

Medical Textiles as Vascular Implants and Their Success to Mimic Natural Arteries

Singh

Wong

Wang

2015

JFB

149

101

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“…Control groups merely containing circumferentially aligned filaments (WSGs) or randomly distributed fibers (ESGs) were prepared with the wall thickness close to TVGs ( Figure 1 c). Kink resistance is one of the critical flexible features of vascular grafts to fit various grafting conditions, in particular in the anatomic location with continuous bending and moving, i.e., carotid artery bypass, axillary femoral, and popliteal regions’ transplantation [ 26 , 27 ]. In these areas, the joint motion may cause the collapse of implants [ 18 ].…”

Section: Resultsmentioning

confidence: 99%

Tri-Layered Vascular Grafts Guide Vascular Cells’ Native-like Arrangement

Yuan

Yao

et al. 2022

Polymers

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Bionic grafts hold great promise for directing tissue regeneration. In vascular tissue engineering, although a large number of synthetic grafts have been constructed, these substitutes only partially recapitulated the tri-layered structure of native arteries. Synthetic polymers such as poly(l-lactide-co-ε-caprolactone) (PLCL) possess good biocompatibility, controllable degradation, remarkable processability, and sufficient mechanical strength. These properties of PLCL show great promise for fabricating synthetic vascular substitutes. Here, tri-layered PLCL vascular grafts (TVGs) composed of a smooth inner layer, circumferentially aligned fibrous middle layer, and randomly distributed fibrous outer layer were prepared by sequentially using ink printing, wet spinning, and electrospinning techniques. TVGs possessed kink resistance and sufficient mechanical properties (tensile strength, elastic modulus, suture retention strength, and burst pressure) equivalent to the gold standard conduits of clinical application, i.e., human saphenous veins and human internal mammary arteries. The stratified structure of TVGs exhibited a visible guiding effect on specific vascular cells including enhancing endothelial cell (EC) monolayer formation, favoring vascular smooth muscle cells’ (VSMCs) arrangement and elongation, and facilitating fibroblasts’ proliferation and junction establishment. Our research provides a new avenue for designing synthetic vascular grafts with polymers.

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“…The bending stiffness of a textile-based stent graft can be evaluated for the flexibility of stent graft [32]. The bending stiffness of BSG was characterized by a Shirley Stiffness Tester and calculated using Equations (3).…”

Section: Heparin Modificationmentioning

confidence: 99%

A heparin-functionalized woven stent graft for endovascular exclusion

Zheng

Chen

et al. 2019

Colloids and Surfaces B: Biointerfaces

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Highlights  A novel seamless bifurcate stent graft (BSG) was developed to avoid the leakage of traditional stent graft.  The BSG with excellent physical properties, which can meet the requirements of transplantation in endovascular graft exclusion.  A very easy drug modification approach by coating mixtures of heparin and silk fibroin solution onto BSG surface was studies.  The cell viability in heparin release of modified BSGs was studied and analyzed. 3 Abstract：With the increase of vascular diseases in recent years, it is of importance to develop an anti-occlusion stent graft, which can meet the requirements of transplants for a long term. In this paper, we describe a silk fibroin (SF)/heparin-functionalized bifurcated stent graft (BSG) using textile forming technology. The BSGs were prototyped based on seamless weaving technology, and the surface was modified with SF-loaded heparin under steam/air treatment to improve their patency. The physical properties such as thickness, water permeability, contact angle, mechanical properties, and in vitro drug release and coagulation time of the BSGs were examined. The results showed that heparin modification can improve its coagulation time, and the water permeability resistance of the BSGs reached 1.154 ± 0.854 mL/(cm 2 ×min), while their thicknesses were just 0.085 ± 0.004 mm. The heparin release of the BSGs showed that the release time was prolonged upon steam treatment by means of the increase in the β-sheet structure and crystallinity of SF. The viability and attachment of human vascular smooth muscle (HVSM) cells cultured in the release of modified BSGs demonstrated that the modified BSGs could significantly inhibit the proliferation of HVSM cells. The heparin-functionalized BSG with satisfactory thickness, water permeability resistance and anti-occlusion function, which has potential applications in the treatment of vascular diseases.

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The influence of textile vascular prosthesis crimping on graft longitudinal elasticity and flexibility

Cited by 9 publications

References 8 publications

Medical Textiles as Vascular Implants and Their Success to Mimic Natural Arteries

Medical Textiles as Vascular Implants and Their Success to Mimic Natural Arteries

Tri-Layered Vascular Grafts Guide Vascular Cells’ Native-like Arrangement

A heparin-functionalized woven stent graft for endovascular exclusion

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