When evaluating the performance of measuring technology for mechanical quantities based on strain gauges (S.G.), one essential advantage is the possibility to realise smallest measurement uncertainties (MU).In these applications, S.G. must be able coping with the further tightening of MU budgets. Thus, two advances in the determination of uncertainty of high precision measurement chains based on S.G., are discussed in here. The two uncertainty contributions, what are not always considered so far, are humidity influences and long-term stability.To support today's sophisticated MU calculations, these two parameters have been further investigated and conclusions are drawn for each of measurement chain elements -reference transducers & precision amplifiers.