Macao's population policy and economic and social development plan always go hand in hand, and as a part of Macao's economic and social development plan, it regulates the population quantity, quality and distribution, creating a suitable population environment for the realization of development goals. Based on the theory of incentive compatibility, this paper discusses the reform path of birth encouragement policy system in Macao. Using sampling survey, through descriptive analysis and binary Logistic regression, this paper analyzes the fertility will of women of childbearing age and its influencing factors from multiple dimensional variables. Through data analysis, Nearly 40% of professional women believe that Macau needs to support relevant fertility support policies in terms of reproduction. The results of binary Logistic regression show that the age of individual and children, the age of one child, the experience of one child, and the difference between household registration nature and job nature in social background factors have a significant impact on the fertility willingness of two children. Based on the research results of women of childbearing age's desire to have two children, this paper puts forward some suggestions on the reform of Macao's fertility encouragement policy system: adhere to the people-centered development thought, improve the medical policy and improve the interest-oriented system of population policy.