The influence of size, depth and histologic characteristics of invasive ductal breast carcinoma on thermographic properties of the breast

Mance, Marko; Bulić, Krešimir; Antabak, Anko; Milošević, Milan

doi:10.17179/excli2019-1600

Cited by 2 publications

(1 citation statement)

References 33 publications

(35 reference statements)

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“…Robotic palpation devices and platforms in the literature do not include tumour-mimicking inclusions that exceed a depth of 15 mm [ 3 , 5 , 7 , 19 , 31 , 32 , 33 , 34 , 35 , 36 , 37 ]. This illustrates a particular gap when it comes to carrying out Clinical Breast Examinations, where the depth of a tumour may exceed 15 mm [ 38 ]. Further, high node heterogeneity may be an important diagnostic feature for breast cancers [ 39 , 40 , 41 , 42 ], meaning that intra-node stiffness is likely to vary and, hence, detecting tactile cues at sub-tumour size scales becomes a useful property that has not been previously developed.…”

Section: Introductionmentioning

confidence: 99%

ESPRESS.0: Eustachian Tube-Inspired Tactile Sensor Exploiting Pneumatics for Range Extension and SenSitivity Tuning

Jenkinson

Conn

Tzemanaki

2023

Sensors

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Optimising the sensitivity of a tactile sensor to a specific range of stimuli magnitude usually compromises the sensor’s widespread usage. This paper presents a novel soft tactile sensor capable of dynamically tuning its stiffness for enhanced sensitivity across a range of applied forces, taking inspiration from the Eustachian tube in the mammalian ear. The sensor exploits an adjustable pneumatic back pressure to control the effective stiffness of its 20 mm diameter elastomer interface. An internally translocated fluid is coupled to the membrane and optically tracked to measure physical interactions at the interface. The sensor can be actuated by pneumatic pressure to dynamically adjust its stiffness. It is demonstrated to detect forces as small as 0.012 N, and to be sensitive to a difference of 0.006 N in the force range of 35 to 40 N. The sensor is demonstrated to be capable of detecting tactile cues on the surface of objects in the sub-millimetre scale. It is able to adapt its compliance to increase its ability for distinguishing between stimuli with similar stiffnesses (0.181 N/mm difference) over a large range (0.1 to 1.1 N/mm) from only a 0.6 mm deep palpation. The sensor is intended to interact comfortably with skin, and the feasibility of its use in palpating tissue in search of hard inclusions is demonstrated by locating and estimating the size of a synthetic hard node embedded 20 mm deep in a soft silicone sample. The results suggest that the sensor is a good candidate for tactile tasks involving unpredictable or unknown stimuli.

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Section: Introductionmentioning

confidence: 99%

ESPRESS.0: Eustachian Tube-Inspired Tactile Sensor Exploiting Pneumatics for Range Extension and SenSitivity Tuning

Jenkinson

Conn

Tzemanaki

2023

Sensors

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Conformable ultrasound breast patch for deep tissue scanning and imaging

Lin

Suh

et al. 2023

Sci. Adv.

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Ultrasound is widely used for tissue imaging such as breast cancer diagnosis; however, fundamental challenges limit its integration with wearable technologies, namely, imaging over large-area curvilinear organs. We introduced a wearable, conformable ultrasound breast patch (cUSBr-Patch) that enables standardized and reproducible image acquisition over the entire breast with less reliance on operator training and applied transducer compression. A nature-inspired honeycomb-shaped patch combined with a phased array is guided by an easy-to-operate tracker that provides for large-area, deep scanning, and multiangle breast imaging capability. The in vitro studies and clinical trials reveal that the array using a piezoelectric crystal [Yb/Bi-Pb(In 1 /2 Nb 1/2 )O 3 -Pb(Mg 1/ 3 Nb 2/3 )O 3 -PbTiO 3 ] (Yb/Bi-PIN-PMN-PT) exhibits a sufficient contrast resolution (~3 dB) and axial/lateral resolutions of 0.25/1.0 mm at 30 mm depth, allowing the observation of small cysts (~0.3 cm) in the breast. This research develops a first-of-its-kind ultrasound technology for breast tissue scanning and imaging that offers a noninvasive method for tracking real-time dynamic changes of soft tissue.

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The influence of size, depth and histologic characteristics of invasive ductal breast carcinoma on thermographic properties of the breast

Cited by 2 publications

References 33 publications

ESPRESS.0: Eustachian Tube-Inspired Tactile Sensor Exploiting Pneumatics for Range Extension and SenSitivity Tuning

ESPRESS.0: Eustachian Tube-Inspired Tactile Sensor Exploiting Pneumatics for Range Extension and SenSitivity Tuning

Conformable ultrasound breast patch for deep tissue scanning and imaging

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