The influence of selenium and selenoproteins on immune responses of poultry and pigs

Dalgaard, Tina Sørensen; Briens, Mickaël; Engberg, Ricarda M.; Lauridsen, Charlotte

doi:10.1016/j.anifeedsci.2018.01.020

Cited by 73 publications

(67 citation statements)

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“…Selenium metabolism has been discussed in the literature with specific regard to the role of Se within the central nervous system [ 174 ]. There are also reviews on the action of Se on productive characteristics, antioxidative status, immune responses and nutrient utilization of poultry [ 175 , 176 ]. Members of this selenoproteome take part in diverse biological pathways and processes in chicken, such as in maintenance of the redox balance; interactions with metals and transport of Se.…”

Section: Effects Of Se Deficiency On Mrna Expression Of Selenoprotmentioning

confidence: 99%

Selenium-Dependent Antioxidant Enzymes: Actions and Properties of Selenoproteins

et al. 2018

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Unlike other essential trace elements that interact with proteins in the form of cofactors, selenium (Se) becomes co-translationally incorporated into the polypeptide chain as part of 21st naturally occurring amino acid, selenocysteine (Sec), encoded by the UGA codon. Any protein that includes Sec in its polypeptide chain is defined as selenoprotein. Members of the selenoproteins family exert various functions and their synthesis depends on specific cofactors and on dietary Se. The Se intake in productive animals such as chickens affect nutrient utilization, production performances, antioxidative status and responses of the immune system. Although several functions of selenoproteins are unknown, many disorders are related to alterations in selenoprotein expression or activity. Selenium insufficiency and polymorphisms or mutations in selenoproteins’ genes and synthesis cofactors are involved in the pathophysiology of many diseases, including cardiovascular disorders, immune dysfunctions, cancer, muscle and bone disorders, endocrine functions and neurological disorders. Finally, heavy metal poisoning decreases mRNA levels of selenoproteins and increases mRNA levels of inflammatory factors, underlying the antagonistic effect of Se. This review is an update on Se dependent antioxidant enzymes, presenting the current state of the art and is focusing on results obtained mainly in chicken.

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Section: Effects Of Se Deficiency On Mrna Expression Of Selenoprotmentioning

confidence: 99%

Selenium-Dependent Antioxidant Enzymes: Actions and Properties of Selenoproteins

et al. 2018

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“…It is also important for a number of physiological processes including regulation and function of the immune system through its incorporation into selenoproteins. Also, Se is involved in the regulation of oxidative stress, redox mechanisms, and other crucial cellular processes involved in innate and adaptive immune response (Dalgaard et al, 2018). Body weight gain, feed conversion efficiency and antioxidant capacity of growing rabbits were improved when offered supplementary dietary Se at a level of 0.24 mg Se/kg Dry Matter (DM) (Zhang et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Effect of Dietary Organic Selenium Supplementation on Growth Performance, Carcass Characteristics and Antioxidative Status of Growing Rabbits

Hassan¹,

Abdel-Azeem²,

Abdel-Rahman³

et al. 2019

jwpr

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Total of 45 weaned male New Zealand White (NZW) rabbits about six weeks old with an average initial body weight 618.11±10.01g were randomly allotted to three dietary groups; the first group fed the basal diet without organic Se, the second fed basal diet +0.2 mg Se-yeast, the third fed basal diet +0.2 mg Se-algae. The obtained results showed that supplementation rabbit diets with Se-yeast and Se-algae have no impact on final body weight and average daily body weight gain. Se-algae supplementation tended to increase (P<0.05) average daily feed intake. Rabbits group fed diet supplemented with Se-yeast achieved better (P<0.05) FCR than that group fed Se-algae (5.06 g feed/g gain). Supplementation of Se-algae at 0.2 mg was the highest (P<0.05) in total protein, albumin, and globulin concentration (7.94, 4.16 and 3.78 g/dl). Diets supplemented with Se-yeast or Se-algae significantly reduced plasma creatinine levels compared to the control group. All recorded values of creatinine and urea concentrations were within the normal ranges. Dietary supplementation with 0.2 mg Se-yeast or Se-algae resulted in a significant (P<0.05) decrease in the activity of AST enzyme. Plasma total cholesterol and plasma LDL levels were significantly decreased (P<0.05) with dietary supplementation with Se-yeast or Se-algae. There was a significant (p<0.05) decrease in plasma MDA level in rabbits fed diets supplemented with Se-yeast or Se-algae. While Catalase activity was significantly (P< 0.05) increased. Rabbits fed diet supplemented with Se-algae was the lowest (P<0.05) group in ether extract meat content while dietary supplementation of Se-algae significantly increased (P<0.05) Se content of rabbits meat of hind leg. Conclusively, Se-yeast and Se-algae can be used as selenium sources in growing rabbit diets without causing any adverse effects on growth performance. Besides, their beneficial effects in improving the antioxidative status.

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“…Up to now, the results of these studies were not considered successful, despite the fact that several substances can inhibit tissue enzymes (for example, citrates and acetates -phosphofructokinase) [44]. To prevent the emergence and development of nutritional myopathies, investigations have been continued in the field of studying an effect of different doses of selenium and vitamin E with regard to sources of these substances, dura-tion of feeding period, feed composition and other factors [1,12,40,43,45,46].…”

Section: Discussionmentioning

confidence: 99%

Myopathy as a Destabilizing Factor of Meat Quality Formation

Семенова

Кузнецова

Насонова

et al. 2019

Teor. prakt. pererab. mâsa (Print)

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This review paper is devoted to myopathy of slaughter animals and poultry, and examines a relationship between fast growth of muscle tissue in hybrid pigs, broiler chickens and turkey, and high frequency of detection of spontaneous or idiopathic myopathies. The development of myopathy reduces consumer and technological properties of meat, and leads to emergence of different pathological conditions (PSE or RSE meat, «destructured meat», «white» or «green» meat, punctate hemorrhage, «wooden breast» and others). Two types of myopathic conditions are examined: myopathies caused by stress in animals and nutritional myopathies, which contribution to meat quality deterioration seems to be determinative. It is shown that the basis of the mechanism of the myopathy development is the mechanism of the successive changes in muscle tissue: damage of cell membranes and release of mitochondrial calcium, which causes hypercontraction, dystrophic changes, atrophy and necrosis of muscle fibers. To alleviate the damaging effect of two types of myopathies, different substances-adaptogens (selenium, vitamin E, flavonoids and others) can be used. It is stated that the requirements of animals in adaptogens change with an increase in the indicators of their productivity. UDC 636.4.084

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The influence of selenium and selenoproteins on immune responses of poultry and pigs

Cited by 73 publications

References 100 publications

Selenium-Dependent Antioxidant Enzymes: Actions and Properties of Selenoproteins

Selenium-Dependent Antioxidant Enzymes: Actions and Properties of Selenoproteins

Effect of Dietary Organic Selenium Supplementation on Growth Performance, Carcass Characteristics and Antioxidative Status of Growing Rabbits

Myopathy as a Destabilizing Factor of Meat Quality Formation

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