The Influence of Peripheral Neuropathy, Gender, and Obesity on the Postural Stability of Patients with Type 2 Diabetes Mellitus

Herrera-Rangel, Aline B.; Aranda-Moreno, Catalina; Mantilla-Ochoa, Teresa; Zainos-Saucedo, Lylia; Jáuregui‐Renaud, Kathrine

doi:10.1155/2014/787202

Cited by 17 publications

(16 citation statements)

References 21 publications

(23 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Patients with peripheral neuropathy might suffer from loss or absence of protective sensation in the lower extremities leading to balance problem [26], risk of foot ulceration [22], pain and frequently disrupts sleep [27], cardiovascular morbidity and mortality [19], reduced quality of life [28] ,and increase costs of treatment [29]. According to reports in the literature, appropriate interventions and screening can reduce ulcers by 60% and amputations by 85% in those with high-risk diabetic neuropathy [30].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of diabetic peripheral neuropathy in Africa: A systematic review and meta-analysis

Shiferaw

Akalu

Work

et al. 2019

Preprint

View full text Add to dashboard Cite

Introduction: Diabetes mellitus is a global health care problem and financially costly. Diabetic peripheral neuropathy is common and frequent cause of morbidity and disability. Despite its serious complications,limited evidence is available on the magnitude of diabetic peripheral neuropathy among patient with diabetes mellitus. Hence the objective of this systematic review and meta-analysis was to estimate the pooled prevalence of diabetic peripheral neuropathy among patients with diabetes mellitus in Africa. Methods: PubMed Scopus Google Scholar Africa journal online WHO afro library and Cochrane review were systematically searched online to retrieve related articles. The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guideline was followed. Heterogeneity across the included studies was evaluated by inconsistency index (I2). Publication bias was examined by funnel plot and Egger regression test. The random-effect model was fitted to estimate the pooled prevalence of diabetic peripheral neuropathy among diabetes mellitus patients. All statistical analysis was done using STATA version 14 software for windows. Results: Twenty-three studies which comprises of 269 691 participants were included in the meta-analysis. The overall pooled prevalence of diabetic peripheral neuropathy was 46% (95% CI:36.21-55.78%). Based on the subgroup analysis the highest magnitude of diabetic peripheral neuropathy was reported in West Africa 49.4% (95% CI: 32.74, 66.06). Conclusion: This study revealed that the overall prevalence of diabetic peripheral neuropathy is relatively high in Africa. Hence, diabetic peripheral neuropathy needs situation based intervention and preventive strategy depending on their country context. Furthermore further meta-analysis study is needed to identify associated factors for the occurrence of diabetic peripheral neuropathy. Key word: diabetic peripheral neuropathy diabetes mellitus Systematic review Meta-analysis Ethiopia.

show abstract

Section: Introductionmentioning

confidence: 99%

Prevalence of diabetic peripheral neuropathy in Africa: A systematic review and meta-analysis

Shiferaw

Akalu

Work

et al. 2019

Preprint

View full text Add to dashboard Cite

show abstract

“…Patients with DPN often suffer from the loss or absence of a protective sensation in the lower extremities leading to balance problems [26], risk of foot ulcerations [22], pain and disrupted sleep patterns [27], cardiovascular morbidity and mortality [19], reduced quality of life [28], and increased cost of treatment [29]. Previous studies have indicated that for those with high-risk diabetic neuropathy, proper management and early screening can minimize the occurrence of ulcers by 60% and amputations by 85% [30].…”

mentioning

confidence: 99%

Prevalence of diabetic peripheral neuropathy in Africa: a systematic review and meta-analysis

et al. 2020

View full text Add to dashboard Cite

Background: Diabetes mellitus (DM) is a global health care problem that can impose a substantial economic burden. Diabetic peripheral neuropathy (DPN) is a common microvascular complication of DM that increases the potential for morbidity and disability due to ulceration and amputation. Though there is a significant amount of variation in the primary studies on DM regarding the prevalence of DPN in Africa. Hence, this study was aimed to estimate the overall prevalence of DPN in DM patients in Africa. Methods: PubMed, Scopus, Google Scholar, African Journals OnLine, WHO African Library, and the Cochrane Review were systematically searched online to retrieve related articles. The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines was followed. Heterogeneity across the included studies was evaluated by the inconsistency index (I 2 ). Publication bias was examined by funnel plot and Egger's regression test.The random-effect model was fitted to estimate the pooled prevalence of diabetic peripheral neuropathy among patients in Africa. The meta-analysis was performed using the STATA™ Version 14 software. Results: Twenty-three studies which includes 269,691 participants were included in the meta-analysis. The overall pooled prevalence of diabetic peripheral neuropathy was 46% (95% CI:36.21-55.78%). Based on the subgroup analysis, the highest prevalence of diabetic peripheral neuropathy in DM patients was reported in West Africa at 49.4% (95% CI: 32.74, 66.06). Conclusion: This study revealed that the overall prevalence of diabetic peripheral neuropathy is relatively high in Africa. Hence, DPN needs situation-based interventions and preventive strategies, which are specific to the country. Further meta-analysis is needed to identify associated factors for the occurrence of diabetic peripheral neuropathy.

show abstract

“…Also, our findings were consistent with the previous literature, showing the influence of obesity on PB only in more severe obese subjects and in situations with greater instability (e.g., ST and eyes closed) [7,12,[35][36][37]. This may be explained by the distribution of FBM [15-17, 32, 33, 38] and mechanical constraints due to severe obesity [8,35,39], but, most of all, we suggested that is related to decreased of muscular strength [34,35] and possible related to fatigue [7], presence of comorbidities [18,[40][41][42][43] and poor physical fitness and PADL [17].…”

Section: Discussionmentioning

confidence: 91%

Effects of obesity on postural balance and occurrence of falls in asymptomatic adults

et al. 2020

View full text Add to dashboard Cite

Introduction: Previous studies suggested that body weight is a strong predictor for postural balance. High body mass index (BMI) presented an association with increased postural sway. However, it seems controversial since studies reported no difference between obese and control group regarding the position of the center of pressure in static postural balance (PB). Also, there is a lack of investigations about the impact of obesity on PB, free of the confound effect of cardiometabolic risk. Objective: The aim of this study was to evaluate the effects of obesity in static PB and occurrence of falls in asymptomatic adults and older adults over 40 years old. Method: The PB of 624 subjects divided into quartiles for BMI, waist-to-hip ratio, waist-to-height and fat body mass as percentage (%FBM) was assessed with and without vision using a force platform. An MANOVA was used to determine if there were differences between quartiles and a logistic regression analysis adjusted for confounders variables were applied to determine the obesity role in the occurrence of falls. Results: We found weak to moderate bivariate correlations between obesity and static PB, which became non-significant after adjustment. We found significant differences between first and fourth quartiles, especially using %FBM. Obesity was not related to the occurrence of falls since the odds ratio values became non-significant for all the indices of obesity after adjustment. Conclusion: Obesity presents little influence on maintaining static PB and seems not to determine the occurrence of falls among subjects over 40 years old.

show abstract

The Influence of Peripheral Neuropathy, Gender, and Obesity on the Postural Stability of Patients with Type 2 Diabetes Mellitus

Cited by 17 publications

References 21 publications

Prevalence of diabetic peripheral neuropathy in Africa: A systematic review and meta-analysis

Prevalence of diabetic peripheral neuropathy in Africa: A systematic review and meta-analysis

Prevalence of diabetic peripheral neuropathy in Africa: a systematic review and meta-analysis

Effects of obesity on postural balance and occurrence of falls in asymptomatic adults

Contact Info

Product

Resources

About