The influence of patient, caregiver, and family factors on symptoms of anxiety and depression in children and adolescents with intractable epilepsy

Puka, Klajdi; Widjaja, Elysa; Smith, Mary Lou

doi:10.1016/j.yebeh.2016.12.011

Cited by 50 publications

(49 citation statements)

References 34 publications

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“…Epilepsy is known to negatively impact parental mental health and the family system, which in turn negatively impacts children's mental health and well-being. 7,[9][10][11][15][16][17] We found that 38% of mothers scored in the at-risk range for major depressive disorder at the time of epilepsy diagnosis, compared to 24% at the 10-year follow-up. Mothers of CWE were not a homogenous group; four subgroups with unique trajectories of depressive symptoms over a 10-year period were identified.…”

Section: Discussionmentioning

confidence: 63%

“…This was the first study, to our knowledge, to prospectively evaluate any aspect of mental health or quality of life among parents of CWE in the long term and to determine whether the course of parental mental health in the long term mirrors the favorable long‐term course of seizure control. Epilepsy is known to negatively impact parental mental health and the family system, which in turn negatively impacts children’s mental health and well‐being . We found that 38% of mothers scored in the at‐risk range for major depressive disorder at the time of epilepsy diagnosis, compared to 24% at the 10‐year follow‐up.…”

Section: Discussionmentioning

confidence: 73%

“…Relative to fathers, mothers of CWE have also been found to have poorer quality of life, and more symptoms of anxiety, depression, and stress; however, it is unclear whether these differences are the result of sex differences or associated with being a primary caregiver . Importantly, the literature to date indicates that poor family environment and parental mental health often have a greater impact on children’s quality of life and health outcomes, relative to epilepsy‐related factors . Some studies have also found that various aspects of family environment act as mediators or moderators in the relationship between parents’ mental health and children’s quality of life .…”

Section: Introductionmentioning

confidence: 99%

“…9,[11][12][13][14] Importantly, the literature to date indicates that poor family environment and parental mental health often have a greater impact on children's quality of life and health outcomes, relative to epilepsy-related factors. 7,[9][10][11][15][16][17] Some studies have also found that various aspects of family environment act as mediators or moderators in the relationship between parents' mental health and children's quality of life. 17 Similarly, parents of children with developmental disabilities and nonneurological chronic conditions, such as asthma, are also at elevated risk of symptoms of depression and anxiety, with family and parent characteristics identified as robust factors associated with child well-being, rather than illness characteristics.…”

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confidence: 99%

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Prevalence and trajectories of depressive symptoms among mothers of children with newly diagnosed epilepsy: A longitudinal 10‐year study

et al. 2019

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Summary Objective Parental depression significantly impacts children’s health and well‐being. This study aimed to (1) estimate the prevalence of depressive symptoms, at six time points, among mothers over the first 10 years after their child was diagnosed with epilepsy; (2) identify trajectories of maternal depressive symptoms over time; and (3) identify baseline factors associated with each trajectory. Methods Data came from the Health‐Related Quality of Life in Children with Epilepsy Study (HERQULES), a Canada‐wide prospective cohort study. Data on child, parent, and family characteristics were collected at the time of diagnosis, and follow‐ups at 0.5, 1, 2, 8, and 10 years. Maternal depressive symptoms were measured using the Center for Epidemiological Studies Depression Scale. Trajectories of depressive symptoms were evaluated using latent class growth modeling, and multinomial logistic regression was used to identify baseline factors associated with each trajectory. Results A total of 356 mothers participated in the study, of whom 57% scored in the at‐risk range for major depression disorder (period‐prevalence). Four unique trajectories were identified as follows: “Low‐Stable” (29% of mothers), “Intermediate‐Stable” (46%), “High‐Stable” (20%), and “High‐Decreasing” (5%). Positive family environment was consistently associated with a better trajectory of depressive symptoms over time; other significant factors included type of seizures, child cognitive comorbidity, maternal age, and maternal education. Significance A substantial proportion of mothers of children with epilepsy are at risk for depression, and this risk is stable over the long term. Family environment at the time of diagnosis has long‐term and persistent effects and may be an ideal target for interventions.

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Section: Discussionmentioning

confidence: 63%

Section: Discussionmentioning

confidence: 73%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Prevalence and trajectories of depressive symptoms among mothers of children with newly diagnosed epilepsy: A longitudinal 10‐year study

et al. 2019

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“…30 In a multicenter study, depressive symptoms in children with epilepsy (ages 6-11 years) were found to be associated with caregiver depression, poor parent relationships, and public support but anxiety symptoms were not specifically associated with any familial factors. 31 In the same study, depressive symptoms in adolescents with epilepsy (ages 12-18 years) were associated with caregiver anxiety, poor family management and social support, and greater family demands. Furthermore, anxiety symptoms in adolescents were also associated with caregiver depression and anxiety.…”

Section: Journal Of Pediatric Epilepsymentioning

confidence: 89%

An Overview of Anxiety Disorders and Depression in Children with Epilepsy: A Literature Review

Gökçen¹,

Turğut

2020

Journal of Pediatric Epilepsy

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Comorbid psychiatric disorders in children with epilepsy have long been a subject of medical literature. Many studies conducted by pediatric neurologists, neurosurgeons, psychiatrists, and psychologists have revealed that psychiatric disorders, including anxiety disorders and depression, are frequently seen in children and adolescents with epilepsy. Due to various etiologies behind epilepsy, causes, manifestation, and treatment of anxiety and depression all have unique aspects. We think there are multiple reasons behind anxiety disorders and depression in children with epilepsy, varying from the physiological nature of the epilepsy itself to the environmental factors such as family, parenting, and social status. In this article, we aim to review the causes, risk factors, and management of anxiety disorders and depression in children with epilepsy.

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Cognitive deficiency, parental relationship, and coping strategies are related with anxiety and depression among parents of children with epilepsy

Ren

Yang

2022

Chronic Diseases and Translational Medicine

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Background: The diagnosis of epilepsy in a child often and understandably causes psychological adjustment difficulties in the parents. To help parents of children with epilepsy cope with stress, it is important to understand how parents cope with the sickness of their child. The objective of this study was to assess factors related to the state of anxiety and depression among parents of children with epilepsy. Methods: The present study was a cross-sectional study, and the data were collected through an anonymous, Internet-based survey platform between October 2018 and October 2019 from 250 participants aged 22-65 years. Participants were invited to fill questionnaires include socioeconomic questionnaire, anxiety, depression, and coping strategies scale. Result: Among the parents of children with epilepsy, 48.8% (122/250) had depressive symptoms (Patient Health Questionnaire-9 [PHQ-9] score >4) and 46.4% (116/250) had anxiety symptoms (7-item Generalized Anxiety Disorder [GAD-7] score >5). Depression among parents of children with epilepsy was significantly associated with comorbidity (odds ratio [OR] = 0.392, 95% CI = 0.182-0.846), a poor parental relationship (OR = 0.283, 95% CI = 0.130-0.614), positive coping (OR = 0.947, 95% CI = 0.903-0.992), and negative coping (OR = 1.287, 95% CI = 1.179-1.405). Anxiety among parents of children with epilepsy was significantly associated with a poor parental relationship (OR = 0.416, 95% CI = 0.207-0.835) and negative coping (OR = 1.155, 95% CI = 1.087-1.228). Conclusions: The present study indicates the importance of couple support and providing effective coping to make parents of children with epilepsy more resilient in the presence of negative life events, especially for parents of children with comorbidity with cognitive deficiency. K E Y W O R D S combability, coping strategies, couple relationship, epilepsy, parents Highlights • Parents of children with epilepsy are at high risk of experiencing anxiety and depression.

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The influence of patient, caregiver, and family factors on symptoms of anxiety and depression in children and adolescents with intractable epilepsy

Cited by 50 publications

References 34 publications

Prevalence and trajectories of depressive symptoms among mothers of children with newly diagnosed epilepsy: A longitudinal 10‐year study

Prevalence and trajectories of depressive symptoms among mothers of children with newly diagnosed epilepsy: A longitudinal 10‐year study

An Overview of Anxiety Disorders and Depression in Children with Epilepsy: A Literature Review

Cognitive deficiency, parental relationship, and coping strategies are related with anxiety and depression among parents of children with epilepsy

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