The influence of obesity and weight gain on quality of life according to the SF-36 for individuals of the dynamic follow-up cohort of the University of Navarra

Barcones-Molero, M.F.; Sánchez‐Villegas, Almudena; Martínez‐González, Miguel Ángel; Bes–Rastrollo, Maira; Martínez-Urbistondo, María; Santabárbara, Javier; Martínéz, J. Alfredo

doi:10.1016/j.rceng.2018.05.005

Cited by 11 publications

(9 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Yet, the present results are valuable from the clinical point of view, providing remarkably similar assessment of the influence of adherence to healthy lifestyle patterns in patients' health as that of the consultation room. The longitudinal multivariate analysis and adjustments, using features related to HRQoL such as waist circumference obesity, MetS features (39), alcohol consumption (40) and total caloric intake (41,42) provide plausibility to the present results.…”

Section: Discussionsupporting

confidence: 61%

Role of NAFLD on the Health Related QoL Response to Lifestyle in Patients With Metabolic Syndrome: The PREDIMED Plus Cohort

Martínez-Urbistondo

Cristóbal²,

Villares³

et al. 2022

Front. Endocrinol.

View full text Add to dashboard Cite

ObjectiveTo evaluate the effect of Non-alcoholic fatty liver disease (NAFLD) status in the impact of lifestyle over Health-related quality of life (HRQoL) in patients with metabolic syndrome (MetS).MethodsBaseline and 1 year follow up data from the PREDIMED-plus cohort (men and women, 55-75 years old with overweight/obesity and MetS) were studied. Adherence to an energy-restricted Mediterranean Diet (er-MeDiet) and Physical Activity (PA) were assessed with a validated screeners. Hepatic steatosis index (HSI) was implemented to evaluate NAFLD while the SF-36 questionnaire provided HRQoL evaluation. Statistical analyses were performed to evaluate the influence of baseline NAFLD on HRQoL as affected by lifestyle during 1 year of follow up.ResultsData from 5205 patients with mean age of 65 years and a 48% of female participants. Adjusted linear multivariate mixed regression models showed that patients with lower probability of NAFLD (HSI < 36 points) were more responsive to er-MeDiet (β 0.64 vs β 0.05 per er-MeDiet adherence point, p< 0.01) and PA (β 0.05 vs β 0.01 per MET-h/week, p = 0.001) than those with high probability for NAFLD in terms Physical SF-36 summary in the 1 year follow up. 10 points of er-MeDiet adherence and 50 MET-h/week were thresholds for a beneficial effect of lifestyle on HRQoL physical domain in patients with lower probability of NAFLD.ConclusionThe evaluation of NAFLD by the HSI index in patients with MetS might identify subjects with different prospective sensitivity to lifestyle changes in terms of physical HRQoL (http://www.isrctn.com/ISRCTN89898870).

show abstract

Section: Discussionsupporting

confidence: 61%

Role of NAFLD on the Health Related QoL Response to Lifestyle in Patients With Metabolic Syndrome: The PREDIMED Plus Cohort

Martínez-Urbistondo

Cristóbal²,

Villares³

et al. 2022

Front. Endocrinol.

View full text Add to dashboard Cite

show abstract

“…This is comparable to other studies of lipoedema patients using either the SF-36 or similar investigative tools [ 4 , 22 , 49 ]. The mean scores across eight domains show more consistency with chronic neuropathic pain patients than obesity patients ( S3 Fig ) [ 50 , 51 ] suggesting similarities with individuals that have a chronic condition.…”

Section: Discussionmentioning

confidence: 99%

Investigation of clinical characteristics and genome associations in the ‘UK Lipoedema’ cohort

Grigoriadis

Sackey²,

Riches³

et al. 2022

PLoS ONE

View full text Add to dashboard Cite

Lipoedema is a chronic adipose tissue disorder mainly affecting women, causing excess subcutaneous fat deposition on the lower limbs with pain and tenderness. There is often a family history of lipoedema, suggesting a genetic origin, but the contribution of genetics is currently unclear. A tightly phenotyped cohort of 200 lipoedema patients was recruited from two UK specialist clinics. Objective clinical characteristics and measures of quality of life data were obtained. In an attempt to understand the genetic architecture of the disease better, genome-wide single nucleotide polymorphism (SNP) genotype data were obtained, and a genome wide association study (GWAS) was performed on 130 of the recruits. The analysis revealed genetic loci suggestively associated with the lipoedema phenotype, with further support provided by an independent cohort taken from the 100,000 Genomes Project. The top SNP rs1409440 (ORmeta ≈ 2.01, Pmeta ≈ 4 x 10–6) is located upstream of LHFPL6, which is thought to be involved with lipoma formation. Exactly how this relates to lipoedema is not yet understood. This first GWAS of a UK lipoedema cohort has identified genetic regions of suggestive association with the disease. Further replication of these findings in different populations is warranted.

show abstract

“…The low rate of completion of anthropometric data in the auto-declared part of the survey did not allow the evaluation of BMI influence in the results. Additionally, information about the interaction between QoL and BMI has been previously reported in a mostly healthy population [ 41 ]. Nevertheless, the comorbid nature of the analyzed cohort, advice to consider the CCI which includes aspects concerning obesity related manifestations and comorbidities instead of BMI.…”

Section: Discussionmentioning

confidence: 99%

Interactions of Comorbidity and Five Simple Environmental Unhealthy Habits Concerning Physical and Mental Quality of Life in the Clinical Setting

Martínez-Urbistondo

Villar

Ramos-López

et al. 2021

IJERPH

View full text Add to dashboard Cite

The objective of this study was to examine the interactions between comorbidity and five lifestyle single habits concerning different subscales of quality of life (QoL). For the study, 302 patients were consecutively recruited at the internal medicine department of a tertiary teaching hospital. Lifestyle habits, comorbidities and QoL were recorded according to validated questionnaires. Five single unhealthy habits, such as tobacco consumption, dietary intake of ultra-processed pastries, raw nuts or carbonated drinks, sleep time and physical activity patterns were selected according to previously published data. The main outcomes of the study were the scores of the eight subscales of the SF-36 QoL survey. The aggregate of unhealthy habits showed statistically significant association to every category in the SF-36 questionnaire, both in the univariate and the multivariate analysis when adjusting by age, sex and comorbidity. An interaction was found between comorbidity and unhealthy habits in both physical and mental summaries of SF-36. In conclusion, the lifestyle assessment according to five unhealthy habits is associated with a worse QoL. The interaction between comorbidity and unhealthy habits is especially clear in diseased patients due to the interplay between illness and lifestyle in the prediction of QoL.

show abstract

The influence of obesity and weight gain on quality of life according to the SF-36 for individuals of the dynamic follow-up cohort of the University of Navarra

Cited by 11 publications

References 40 publications

Role of NAFLD on the Health Related QoL Response to Lifestyle in Patients With Metabolic Syndrome: The PREDIMED Plus Cohort

Role of NAFLD on the Health Related QoL Response to Lifestyle in Patients With Metabolic Syndrome: The PREDIMED Plus Cohort

Investigation of clinical characteristics and genome associations in the ‘UK Lipoedema’ cohort

Interactions of Comorbidity and Five Simple Environmental Unhealthy Habits Concerning Physical and Mental Quality of Life in the Clinical Setting

Contact Info

Product

Resources

About