The influence of maternal and paternal factors on time to pregnancy--a Dutch population-based birth-cohort study: the GECKO Drenthe study

Mutsaerts, Meike; Groen, Henk; Huiting, H. G.; Kuchenbecker, Walter K. H.; Sauer, Pieter J. J.; Land, Jolande; Stolk, Ronald P.; Hoek, Annemieke

doi:10.1093/humrep/der429

Cited by 130 publications

(87 citation statements)

References 38 publications

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“…15, 16 The analysis was performed on the whole group and also on each diagnostic group. Treatment strategies have changed over time from more to less intensive treatments, which resulted in reduced mortality.…”

Section: Discussionmentioning

confidence: 99%

Reproductive Patterns Among Childhood and Adolescent Cancer Survivors in Sweden: A Population-Based Matched-Cohort Study

Armuand

Skoog-Svanberg

Bladh

et al. 2017

JCO

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To compare the probability of a first live birth, age at time of birth, and time between diagnosis/ referent date and birth between childhood and adolescent cancer survivors and an age-matched comparison group. Materials and MethodsA total of 1,206 survivors was included in the study, together with 2,412 age-matched individuals from the general population. A Cox proportional hazards model was used to investigate first live birth after diagnosis/referent date. Data were stratified by sex, age at diagnosis, and diagnostic era (ie, diagnosis before 1988 v in 1988 or later). ResultsOverall, the probability of having a first live birth (hazard ratio [HR]) was significantly lower; men had lower HRs than women (HR, 0.65 v 0.79). There were no significant differences in the probability of having a first live birth among women diagnosed during adolescence (HR, 0.89), but the HR was lower among women with childhood cancers (HR, 0.47). Among male survivors, the situation was the opposite; men diagnosed during adolescence had lower HRs than survivors of childhood cancer (HR, 0.56 v 0.70). Examination of the data from the two diagnostic eras (before 1988 and 1988 or later) shows that the HR increased among female survivors after 1988 (HR, 0.71 v 0.90) and decreased among male survivors (HR, 0.72 v 0.59). A shorter time had elapsed between diagnosis/ referent date and the birth of a first child among both male and female survivors compared with controls. In addition, female survivors were younger at time of birth. ConclusionThe study demonstrates reduced probability of having a first live birth among cancer survivors diagnosed during childhood or adolescence; men were particularly vulnerable.

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Section: Discussionmentioning

confidence: 99%

Reproductive Patterns Among Childhood and Adolescent Cancer Survivors in Sweden: A Population-Based Matched-Cohort Study

Armuand

Skoog-Svanberg

Bladh

et al. 2017

JCO

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“…In studies that controlled for female age, successful pregnancy was higher in those with a younger male partner. Thus, initiating pregnancy before the age of 30 for women and before 35 for men may provide the highest level of fecundity (42).…”

Section: Discussionmentioning

confidence: 99%

Lifestyle Related Fertility Disorders in North Jordan: Potential for Improvement

Hamadneh¹,

Amarin²,

Hamadneh³

et al. 2017

International Journal of Women’s Health and Reproduction Scienc

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IntroductionCurrent evidence indicates a 9% prevalence of infertility (1). Patients that are hoping to get pregnant might wonder about their fertility and whether they can improve it. There is an increasing body of evidence that lifestyle factors can influence reproductive health. The post-industrial era is associated with an excessive exposure to certain lifestyle factors and behaviors that have the potential for a positive or negative effect on reproductive performance (2). Some factors might be beyond patients' control, such as medical issues that affect both male and female fertility, but other lifestyle factors, such as nutrition, weight, exercise, psychological stress, and age of starting a family can be modifiable (2).Negative effects of lifestyle factors such as environmental and occupation exposure, illicit drug use, cigarette smoking, medications, weight management, exercise, alcohol and caffeine consumption are well documented (3-6). Lifestyle-related fertility disorders were estimated to be responsible for 5% of all cases of subfertility (7). To enhance fertility, such lifestyle factors, once identified, can be modified.The findings of the effect of body weight on fertility are firmly established in both sexes. Pathophysiologically, being over or underweight would lead to hormonal changes that would lead to oligomenorrhea and anovulation with subsequent subfertility (8-14). Studies investigating sporting behavior indicate that excessive sport, in terms of frequency, duration and intensity have a negative effect on hormone balance and reproductive performance. The findings of these studies were independent of the confounding factors of age, smoking or body mass index (BMI) (15)(16)(17)(18)(19).There is a plethora of studies that document the detrimental effect of smoking on both male (20,21) and female reproductive performance (22,23). Research indicates that smoking impairs sperm count, motility, morphology and fertilization capacity (20). Women smokers have a significantly smaller number of pregnancies and a higher incidence of miscarriages and ectopic pregnancies (23).Commonly encountered drugs and medications may be detrimental to semen parameters and male sexual performance (24). These agents may exert a gonadotoxic effect on the testicles, alter the hypothalamic-pituitary-gonadal axis, and impair ejaculation, erectile function and libido (25).Recreational drugs can affect male fertility. The long- AbstractObjectives: To explore the prevalence rates of lifestyle practices linked to fertility disorders. Materials and Methods: A cross-sectional descriptive study, using a validated questionnaire, was conducted among sub-fertile couples attending the fertility center at Jordan University of Science and Technology between February 2013 and August 2014. Results: A total of 126 couples took part in the study. The average length of sub-fertility was 4.2 years. The mean age of the women was 31 years, of whom 70% were <35 years of age. Over 6% engaged in regular sporting activity. Less than 1% of women smo...

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“…In a study conducted in 7393 women, women consuming excessive amounts of alcohol had infertility-related scanning more often than those who consumed alcohol moderately (RR=1.59, CI 1.09-2.31) and those who consumed little alcohol (RR=0.64, CI 0.46-0.9). In addition, increased frequency of alcohol intake, from once a week to 5 times a week, lengthened the time for conception (p=0.04; CI-0.95, CI=0.85-1.10) 6 . Researchers thought that alcohol caused fl uctuations in the hormonal levels and inhibited ovulation and folliculogenesis 7 .…”

Section: Alcohol Consumptionmentioning

confidence: 99%

Effect of modification of lifestyle on reproductive potential

Aydin¹,

Karadağ²,

Demir³

et al. 2014

Kafkas J Med Sci

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The influence of maternal and paternal factors on time to pregnancy--a Dutch population-based birth-cohort study: the GECKO Drenthe study

Cited by 130 publications

References 38 publications

Reproductive Patterns Among Childhood and Adolescent Cancer Survivors in Sweden: A Population-Based Matched-Cohort Study

Reproductive Patterns Among Childhood and Adolescent Cancer Survivors in Sweden: A Population-Based Matched-Cohort Study

Lifestyle Related Fertility Disorders in North Jordan: Potential for Improvement

Effect of modification of lifestyle on reproductive potential

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