The influence of implant surface roughness on decontamination by antimicrobial photodynamic therapy and chemical agents: A preliminary study in vitro

Balderrama, Ísis de Fátima; Stuani, Vitor de Toledo; Cardoso, Matheus Völz; Oliveira, Rodrigo Cardoso de; Lopes, Marcelo Milanda Ribeiro; Greghi, Sebastião Luiz Aguiar; Passanezi, Sant’Ana Adriana Campos

doi:10.1016/j.pdpdt.2020.102105

Cited by 6 publications

(3 citation statements)

References 51 publications

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“…Metal instruments and ultrasonic scalers with or without local antiseptic therapy can increase the surface roughness of implants, and non-metallic curettes do not provide effective removal of the microbial plaque. Chemical agents do not allow complete removal of bacterial contamination and may contaminate the implant surface with different chemical agents [9]. Diode lasers with different wavelengths have been effective in decontaminating implants and inhibiting lipopolysaccharide (LPS)-induced macrophage activation and consequent attenuation of the inflammatory response.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Dual-Wavelength Laser Irradiation against Implant-Adherent Biofilms of Staphylococcus aureus, Escherichia coli, and Candida albicans for Improved Antimicrobial Photodynamic Therapy

Afrasiabi,

Benedicenti,

Signore

et al. 2024

Bioengineering

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The efficiency of antimicrobial photodynamic therapy (PDT) might be improved by using multiple wavelengths. This study investigates the sensitivity of implant-adherent biofilms of Staphylococcus aureus, Escherichia coli, and Candida albicans to indocyanine green (ICG)-808 nm diode laser, toluidine blue O (TBO)-635 nm diode laser, and hydrogen peroxide (HP)-980 nm diode laser and their combination when irradiated with dual-wavelength laser irradiation (simultaneously 980–635 nm or 980–808 nm). After an incubation period of 72 h, the infected implants were randomly divided into seven different treatment modalities: Control, HP, HP-PDT, TBO-PDT, HP-TBO-PDT, ICG-PDT, and HP-ICG-PDT. After the treatments, the colony-forming units (CFUs)/mL and reactive oxygen species (ROS) generation were determined. All evaluated disinfection methods were significantly effective against the three investigated bacteria compared to the control. The combined treatment of HP-ICG-PDT or HP-TBO-PDT had the greatest antibacterial effect compared to each treatment alone. There were statistical differences between HP-ICG-PDT and ICG-PDT or HP-TBO-PDT and TBO-PDT for all three bacteria studied. PDT with simultaneous dual-wavelength laser irradiation is an efficient strategy to improve the therapeutic effect of PDT.

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Section: Introductionmentioning

confidence: 99%

Simultaneous Dual-Wavelength Laser Irradiation against Implant-Adherent Biofilms of Staphylococcus aureus, Escherichia coli, and Candida albicans for Improved Antimicrobial Photodynamic Therapy

Afrasiabi,

Benedicenti,

Signore

et al. 2024

Bioengineering

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“… 35 Surface parameters obtained were R q (root mean square deviation), R a (arithmetic mean deviation), R sk (skewness), and R ku (kurtosis). 36 Data was obtained by analyzing a 5 μm × 5 μm area from the surface of each gel type. Both the rms surface roughness, R q , and arithmetic surface roughness, R a, values of the gels were quite similar, within the range of ∼ 20–25 nm ( Figure 5 ; Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

“…Surface roughness was analyzed in NanoScope Analysis which measured the roughness parameters . Surface parameters obtained were R q (root mean square deviation), R a (arithmetic mean deviation), R sk (skewness), and R ku (kurtosis) . Data was obtained by analyzing a 5 μm × 5 μm area from the surface of each gel type.…”

Section: Resultsmentioning

confidence: 99%

Additive Manufacturing of Viscoelastic Polyacrylamide Substrates for Mechanosensing Studies

et al. 2022

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Effectiveness of mechanical and chemical decontamination methods for the treatment of dental implant surfaces affected by peri‐implantitis: A systematic review and meta‐analysis

Hart,

Wells,

Tsigarida

et al. 2024

Clinical & Exp Dental Res

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ObjectiveTo assess which decontamination method(s) used for the debridement of titanium surfaces (disks and dental implants) contaminated with bacterial, most efficiently eliminate bacterial biofilms.Material and MethodsA systematic search was conducted in four electronic databases between January 1, 2010 and October 31, 2022. The search strategy followed the PICOS format and included only in vitro studies completed on either dental implant or titanium disk samples. The assessed outcome variable consisted of the most effective method(s)—chemical or mechanical— removing bacterial biofilm from titanium surfaces. A meta‐analysis was conducted, and data was summarized through single‐ and multi‐level random effects model (p < .05).ResultsThe initial search resulted in 5260 articles after the removal of duplicates. After assessment by title, abstract, and full‐text review, a total of 13 articles met the inclusion criteria for this review. Different decontamination methods were assessed, including both mechanical and chemical, with the most common method across studies being chlorhexidine (CHX). Significant heterogeneity was noted across the included studies. The meta‐analyses only identified a significant difference in biofilm reduction when CHX treatment was compared against PBS. The remaining comparisons did not identify significant differences between the various decontamination methods.ConclusionsThe present results do not demonstrate that one method of decontamination is superior in eliminating bacterial biofilm from titanium disk and implant surfaces.

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The influence of implant surface roughness on decontamination by antimicrobial photodynamic therapy and chemical agents: A preliminary study in vitro

Cited by 6 publications

References 51 publications

Simultaneous Dual-Wavelength Laser Irradiation against Implant-Adherent Biofilms of Staphylococcus aureus, Escherichia coli, and Candida albicans for Improved Antimicrobial Photodynamic Therapy

Simultaneous Dual-Wavelength Laser Irradiation against Implant-Adherent Biofilms of Staphylococcus aureus, Escherichia coli, and Candida albicans for Improved Antimicrobial Photodynamic Therapy

Additive Manufacturing of Viscoelastic Polyacrylamide Substrates for Mechanosensing Studies

Effectiveness of mechanical and chemical decontamination methods for the treatment of dental implant surfaces affected by peri‐implantitis: A systematic review and meta‐analysis

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