The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata

Biological and Hematological Responses of Biomphalaria Alexandrina to Mycobiosynthsis Silver Nanoparticles

“…The light microscopy photographs of untreated B. alexandrina hemolymph showed two morphologically distinct types of hemocytes; granulocytes and hyalinocytes. This was agreed with Sminia and Van der Knaap (1987), Lie et al (1987), Barraco et al (1993) and Serrano et al (2002).…”

utaneous verrucose phaeohyphomycosis due to Exophiala oligosperma in an immunocompetent host

“…In high concentrations, hydrocortisone attenuates the cells of defense and delays the migration of phagocytic cells to the traumatized area by reducing vasodilatation and the subsequent vascular permeability. Other effects of steroids on fungi are growth stimulating, change in morphology favoring the change from yeast to hyphae, and resistance to antimycotics, making the fungus less vulnerable to osmotic stress in the presence of the antimycotic [12,13]. With all these described effects, the steroid may aggravate the clinical course of the infection.…”

“…The patient received amphotericin B treatment after diagnosis and was cured after ten months. Another eight cases of E. oligosperma infection were reported between 2007 and 2016 and showed global distribution, including Japan, Spain, India, and Taiwan [4,[13][14][15][16]. Most of the patients had immunosuppression status.…”