The Influence of Heat Treatment in Liquid Whey at Various pH on Immunoglobulin G and Lactoferrin from Yak and Cows’ Colostrum/Milk

Xiaoyun, Shimo Peter Shimo Wu; Lin, Ding xuezhi Xiong

doi:10.4172/2157-7110.1000503

Cited by 3 publications

(2 citation statements)

References 60 publications

(74 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These results largely agree with the study by Shimo et al, who recorded significant aggregation and denaturation of lactoferrin at temperatures above 63 • C, especially when pH was increased as well. Below 63 • C, no significant denaturation occurred (70). Other immunological compounds in colostrum such as cytokines were studied as well.…”

Section: Effects On Serum Igg and Apparent Efficiency Of Absorptionmentioning

confidence: 99%

A Scoping Review of On-Farm Colostrum Management Practices for Optimal Transfer of Immunity in Dairy Calves

et al. 2021

View full text Add to dashboard Cite

Newborn calves are agammaglobulinemic and rely for their first immune protection almost completely on the transfer of immune constituents via colostrum. Inadequate colostrum management practices such as on-farm colostrum storage practices and colostrum feeding methods could affect immune components in colostrum and subsequently immune status of the newborn calf. We conducted a scoping review to identify all literature on the interactions between several colostrum management factors and immunological colostrum quality and passive transfer of immunity. Three major stages were defined: milking methods, colostrum treatment and storage, and administration procedures. Separate CAB Abstracts searches were performed for each of the subjects of interest. The search process was completed on November 9, 2020. Colostrum should be milked as soon as possible, as IgG concentration diminishes over time, probably due to dilution. To minimize bacterial contamination, it is advised to pasteurize colostrum in small batches at maximal 60°C for 30 or 60 min. Freeze/thawing of colostrum does not or only slightly affect IgG concentrations, as long as thawing is done au bain-marie and temperature does not exceed 40°C. In on-farm situations, it is difficult to determine the volume that should be fed as the variables contributing to the absorption of IgG by the newborn calf are many and include the quality of the colostrum, the bacterial contamination, the time interval between birth and first moment of feeding and the weight of the calf. Despite all knowledge regarding optimal colostrum management strategies, it remains challenging to predict the effects of certain colostrum management choices in field conditions. Therefore, we recommend measuring the colostral quality, weighing the newborn calf, adjusting the feeding volume accordingly to ensure optimal colostrum intake for each calf.

show abstract

Section: Effects On Serum Igg and Apparent Efficiency Of Absorptionmentioning

confidence: 99%

A Scoping Review of On-Farm Colostrum Management Practices for Optimal Transfer of Immunity in Dairy Calves

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Whereas in adults, colostrum promotes healing of the GI tract and protects against gut pathogens (bacteria, viruses, fungi, yeast, mold, etc. ), and leaky gut syndrome ( Shah, 2000 ; Hurley and Theil, 2011 ; Osada et al., 2014 ; Wu Xiaoyun and Xiong Lin, 2015 ). The major bioactive components of bovine colostrum and their functions in children and adults are summarized in Table 1 .…”

Section: Introductionmentioning

confidence: 99%

Therapeutic Applications of Human and Bovine Colostrum in the Treatment of Gastrointestinal Diseases and Distinctive Cancer Types: The Current Evidence

et al. 2020

View full text Add to dashboard Cite

The incidence of gastrointestinal disorders (GID) and cancers is escalating all over the world. Limited consumption of colostrum by newborns not only weakens the immune system but also predisposes infants to microbial infections. Colostrum is nature’s perfect food, sometimes referred to as the ‘elixir of life’. Breast-fed infants have a lower incidence of GI tract infections than infants fed formula or cow’s milk. As per WHO statistics, cancer is the most prevalent disease globally and causes 9.6 million deaths worldwide. The current strategies for treating cancer include chemotherapy, radiation, and surgery. However, chemotherapy and radiation exposure are usually associated with serious long-term side effects and deterioration in the quality of life (QOL) of patients. Furthermore, the hospitalization and medication costs for treating cancers are exorbitant and impose high economic burden on healthcare systems. People are desperately looking for cost-effective and affordable alternative therapies for treating GID and cancers. Therefore, there is an urgent need for clinically evaluating the anticancer compounds isolated from plants and animals. Such therapies would not only be economical and have fewer side effects, but also help to improve the QOL of cancer patients. Recently, bovine colostrum (BC) has caught the attention of many investigators to explore its anticancer potential in humans. BC impregnated dressings are highly effective in treating chronic wounds and diabetic foot ulcer. BC is rich in lactoferrin, a glycoprotein with strong antioxidant, anti-inflammatory, anti-cancer, and anti-microbial properties. Intravaginal application of BC tablets is effective in causing the regression of low-grade cervical intraepithelial neoplasia. The underlying mechanisms of BC at cellular, genetic, and molecular levels remain to be ascertained. Oral BC supplement is well-tolerated, but some people may experience problems such as flatulence and nausea. Well-designed, randomized, placebo-controlled, clinical trials are needed to access the therapeutic potential, long-term safety, and optimal doses of BC products. This review is aimed to highlight the anticancer potential of BC and its components, and the therapeutic applications of BC supplements in treating gastrointestinal diseases in children and adults. We also discuss the health promotion benefits and therapeutic potential of BC nutraceuticals in reducing the incidence of non-communicable diseases.

show abstract

Colostrum: A New Golden Era in Health and Disease

Singh¹,

Kushwaha²

2021

AJRC

View full text Add to dashboard Cite

Colostrum is the first fluid yielded from the mammary glands of mammals after parturition and is intended for ingestion by the newborn during the first hours of life. It is a complex biological fluid, contains immune and growth factors which helps in the development of immunity in the newborn. It contains Immunoglobulin’s that act as natural anti-microbial agents to actively stimulate the maturation of an infant’s immune system. It is used for treatment of many GIT diseases, Respiratory diseases, Cardiovascular and Metabolic disorders. Colostrum shows great beneficial effect as immunomodulator and anticancer agent. As antiviral agent there is a great scope in colostrum supplements. In this article, the current understanding of the composition of colostrum, i.e. carbohydrates, proteins, growth factors, enzymes, enzyme inhibitors, nucleotides and nucleosides, cytokines, fats, vitamins and minerals, is reviewed. Besides providing immune support, colostrum has remarkable muscular-skeletal repair and growth capabilities. These growth factors have significant muscle and cartilage repair characteristics. They promote wound healing with practical implications for trauma and surgical patients. Colostrum growth factors have multiple regenerative effects that extend to all structural body cells, such as the gut. Colostrum also provides immunological balance, increases energy and reduces inflammation and illness.

show abstract

The Influence of Heat Treatment in Liquid Whey at Various pH on Immunoglobulin G and Lactoferrin from Yak and Cows’ Colostrum/Milk

Cited by 3 publications

References 60 publications

A Scoping Review of On-Farm Colostrum Management Practices for Optimal Transfer of Immunity in Dairy Calves

A Scoping Review of On-Farm Colostrum Management Practices for Optimal Transfer of Immunity in Dairy Calves

Therapeutic Applications of Human and Bovine Colostrum in the Treatment of Gastrointestinal Diseases and Distinctive Cancer Types: The Current Evidence

Colostrum: A New Golden Era in Health and Disease

Contact Info

Product

Resources

About