The influence of gender on the outcome of coronary artery bypass surgery

Abramov, Dan; Tamariz, Miguel; Sever, Jeri; Christakis, George T.; Bhatnagar, Gopal; Heenan, Amie L; Goldman, Bernard S.; Fremes, Stephen E.

doi:10.1016/s0003-4975(00)01563-0

Cited by 201 publications

(189 citation statements)

References 15 publications

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“…These animal studies are consistent with human studies indicating that women have a significantly greater risk potential compared with men and worse outcomes after cardiac surgery [3,4].…”

supporting

confidence: 86%

Age- and Gender-Related Differences in Mitochondrial Oxygen Consumption and Calcium With Cardioplegia and Diazoxide

McCully

Rousou

Parker

et al. 2007

The Annals of Thoracic Surgery

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Background-We have recently shown that the cardioprotection afforded by cardioplegia is affected by age and gender and is less effective in the aged female rabbit heart compared with the aged male rabbit heart. We hypothesized that these differences were due to age and gender-specific modulation of mitochondrial oxygen consumption and mitochondrial free matrix calcium ([Ca 2+ ] Mito ) content occurring during early reperfusion.

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“…These animal studies are consistent with human studies indicating that women have a significantly greater risk potential compared with men and worse outcomes after cardiac surgery [3,4].…”

supporting

confidence: 86%

Age- and Gender-Related Differences in Mitochondrial Oxygen Consumption and Calcium With Cardioplegia and Diazoxide

McCully

Rousou

Parker

et al. 2007

The Annals of Thoracic Surgery

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“…The survival of women was even better than in the men after adjusting for risk factors in some of the studies, despite the disparities in the outcome of coronary revascularization between women and men [14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Health-related quality of life in patients with coronary artery disease after coronary revascularization

Tasić¹,

Lazarević

Stojanović

et al. 2013

Open Medicine

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AbstractThe aim of this study was to investigate the quality of life (HRQoL) in coronary artery disease(CAD) patients, admitted for rehabilitation within 3 months after an acute coronary event, in relation to treatment strategy [conservative treatment without revascularization (WR), percutaneous transluminal coronary angioplasty (PTCA), coronary artery bypass graft (CABG)]. Methods: Overall 719 consecutive CAD patients were involved in the study: WR (n=170), PTCA (n=226), CABG (n=323). HRQoL was estimated using the SF-36 questionnaire for total QoL and its two dimensions for physical and mental health [physical and mental component scores (PCS, MCS)]. Sexual dysfunction was assessed using the ASEX scale. Results: Significantly higher PCS, MCS and total SF-36, but lower ASEX score, were found in men compared with women. The ASEX score was significantly affected by age. Significantly higher PCS was found in PTCA group compared with that of CABG group. In multivariate analysis a significant positive association was obtained between PCS/MCS and male sex, between regular exercise, hyperlipoproteinemia, and permanent stress. ASEX was significantly positively associated with the age, CHF and non smoking. Conclusion: The results of this study have demonstrated significantly better HRQoL in men, younger CAD patients, patients who underwent PTCA and in patients without self-reported exposition to stress.

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“…of Thoracic Surgeons National Cardiac Surgery Database provides evidence that women undergoing coronary artery bypass grafting surgery have a significantly higher operative mortality rate (4.5%) compared with men (2.6%; p < 0.0001) [4,5]. Multivariate analysis also shows that women have higher mortality rates than equally matched men in low-risk and medium-risk groups [1,6].…”

mentioning

confidence: 99%

Age- and Gender-Related Differences in Ischemia/Reperfusion Injury and Cardioprotection: Effects of Diazoxide

McCully

Toyoda

Wakiyama

et al. 2006

The Annals of Thoracic Surgery

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The influence of gender on the outcome of coronary artery bypass surgery

Cited by 201 publications

References 15 publications

Age- and Gender-Related Differences in Mitochondrial Oxygen Consumption and Calcium With Cardioplegia and Diazoxide

Age- and Gender-Related Differences in Mitochondrial Oxygen Consumption and Calcium With Cardioplegia and Diazoxide

Health-related quality of life in patients with coronary artery disease after coronary revascularization

Age- and Gender-Related Differences in Ischemia/Reperfusion Injury and Cardioprotection: Effects of Diazoxide

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