The Influence of Environmental Temperature on the Level of Plasma Antidiuhetic Substances in the Rat

Robinson, Kathleen; Wv, MacFarlane

doi:10.1071/bi9560130

Cited by 13 publications

(2 citation statements)

References 11 publications

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“…1967) and thereby reduce salivary evaporation. Increased secretion of ADH has been observed in rats during heat stress (Itoh 1954;Robinson and Macfarlane 1956).…”

Section: Discussionmentioning

confidence: 97%

Evaporative cooling in the rat: Effects of dehydration

Em¹,

Fr²

1970

Can. J. Physiol. Pharmacol.

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STRICKER, E. M., AVD HAINSWORTH, F. R. 1970. Evaporative cooling in the rat: Effects of dehydration.Can. J. Physiol. Plaarmacol. 48,[18][19][20][21][22][23][24][25][26][27] Previous investigations dcmonstrrited that the water loss of rats associated with increased sajivary evaporation during heat stress is derived from both intracellular and intravascular sources. The present studies indicate that sufficient delaydration of either fluid compartment will impair temperature regulation. Salivary excretion from all dehydrated rats was virtually abolished at ambient temperatures below 38-40 "C, but temperature regulation was still possible if a large temperature gradient existed between the animals and the environment. Above these ambient temperatures, where increased evaporation is essential to survival, the rate of evaporative water loss returned to normal. However, body water reservoirs in dehydrated rats were rapidly depleted, salivary evaporation could not be maintained, and survival times were shortened. In contrast, access to drinking water significantly increased thermal tolerance. These results emphasize the importance of adequate body fluid hydration for evaporative cooling through saliva spreading by rats in the heat. In addition, they indicate that allocation of body water for evaporation takes precedence over conflicting demands for water conscrvation during heat stress.

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“…1967) and thereby reduce salivary evaporation. Increased secretion of ADH has been observed in rats during heat stress (Itoh 1954;Robinson and Macfarlane 1956).…”

Section: Discussionmentioning

confidence: 97%

Evaporative cooling in the rat: Effects of dehydration

Em¹,

Fr²

1970

Can. J. Physiol. Pharmacol.

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“…Subsequently several attempts have been made to increase the sensitivity of rats to exogenous ADH so that physiological concentrations of the hormone could be measured in plasma (e.g. Dicker, 1953;Robinson & MacFarlane, 1956; Dettelbach, 1958) but in general, such modifications have not been successful. Nevertheless, there are several reports of rats, prepared in the manner of Jeffers et al (1942), which showed significant responses to small doses of ADH (Gupta, Chaudhury & Chhuttani, 1967;Forsling, Jones & Lee, 1968).…”

Section: Introductionmentioning

confidence: 99%

Increased sensitivity of ADH bio‐assay in rats by change in diet.

Kappagoda¹,

M²

1980

The Journal of Physiology

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SUMMARY1. Water-loaded rats anaesthetized with ethanol were used for the detection of antidiuretic hormone (ADH).2. Litter-mates were divided into groups and placed on different diets during the fourth week of life directly after weaning, and maintained on their respective diets for approximately 1 month and their sensitivity to vasopressin was determined.3. The rats maintained on a diet of only vegetable or vegetable plus casein supplement showed a greater sensitivity to exogenous vasopressin than rats maintained on a standard laboratory diet (pellets).4. It is proposed that the quantitative relationship between ADH and urine flow is dependent upon the previous history of water consumption.

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The Assay of Neurohypophysial Hormones in Blood and Other Body Fluids

Fitzpatrick¹,

Bentley²

1968

Neurohypophysial Hormones and Similar Polypeptides

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The Influence of Environmental Temperature on the Level of Plasma Antidiuhetic Substances in the Rat

Cited by 13 publications

References 11 publications

Evaporative cooling in the rat: Effects of dehydration

Evaporative cooling in the rat: Effects of dehydration

Increased sensitivity of ADH bio‐assay in rats by change in diet.

The Assay of Neurohypophysial Hormones in Blood and Other Body Fluids

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