The influence of environmental risk factors in the development of ALS in the Mediterranean Island of Cyprus
Ellie Mitsi,
Christiana C. Christodoulou,
Paschalis Nicolaou
et al.
Abstract:IntroductionAmyotrophic lateral sclerosis (ALS) is a devastating, uniformly lethal degenerative disease of motor neurons, presenting with relentlessly progressive muscle atrophy and weakness. The etiology of ALS remains unexplained for over 85% of all cases, suggesting that besides the genetic basis of the disease, various environmental factors are implicated in the pathogenesis of ALS. This study aimed to investigate the contribution of known environmental risk factors of ALS in the Cypriot population.Methods… Show more
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