The Influence of Dentine on the pH of Calcium Hydroxide, Chlorhexidine Gel, and Experimental Bioactive Glass‐Based Root Canal Medicament

Abstract

Objectives. To evaluate the influence of dentine on the pH of different medications in standardized simulated canals. Materials and Methods. Forty resin blocks were divided into groups with and without dentine powder, as follows: 2% chlorhexidine gel; 2% chlorhexidine gel associated with calcium hydroxide PA; calcium hydroxide PA delivered in propylene glycol 600; and NPG delivered in distilled water. The dentine powder was obtained from the root dentine of bovine teeth and added to the medications. The simulated canals were placed in containers with 1.5 mL of deionized water and pH was monitored in multiple intervals, up to 30 days. The mean pH values were calculated and submitted to statistical analysis using paired Student's t-test and ANOVA complemented by the Tukey test (p < 0.05). Results. There was no statistical difference between the groups with and without dentine powder (p > 0.05). The pH values of calcium hydroxide were significantly higher than those of NPG in the first 24 hours (p < 0.05). After 7 days, both behaved in a similar manner. Conclusion. The addition of dentine powder to the medications evaluated did not alter the pH of the external solution in any of the time points tested.

Effect of triple antibiotic paste and calcium hydroxide on the rate of healing of periapical lesions: A systematic review

“…[ 28 ] Another possible reason is the buffering capacity of dentin which brings down the alkalinity of calcium hydroxide rendering it less effective. [ 29 ] These cases were further treated with triple antibiotic paste.…”

Ions Release and pH of Calcium Hydroxide-, Chlorhexidine- and Bioactive Glass-Based Endodontic Medicaments

“…In the experimental glass there was an interruption of release on the 14th day, but release began again on the 21st day and its levels were equal to the release at 7 days. A possible explanation for this is that the chemical stability of phosphate glasses increases when niobium is added (24,25), thus leading to a slightly slower release of ions. A higher level of sodium ion release was observed for the groups CHX and GB, with a statistically higher immediate level of release for the glass than for all the other groups.…”

Influence of chlorhexidine and zinc oxide in calcium hydroxide pastes on pH changes in external root surface

“…Such results concur with those of other studies that found pH values between 9 and 12. 32,33,34,35 However, Carvalho et al 36 observed that when CHX was used as the vehicle, the peak pH was achieved immediately after preparation of the medication (pH = 9); after 7 days, the pH was neutral. These authors have questioned the efficacy of the combination of CHX and CH.…”