The Temporomandibular Joint (TMJ) is a complex joint, with distinct anatomical and functional characteristics, making it difficult to treat. Many authors, beginning in the early 20 th century, reported techniques for TMJ reconstruction, aiming at recovering its shape and ideal function. After conducting studies on CT scans of 50 TMJs, A system for customized TMJ prostheses (temporomandibular joint) was developed in PEEK Lt1 20%Ba with 2/3 of the ramus length. The glenoid cavity was shaped into a flattened plane, with removal of the articular eminence of the temporal bone, at an angle of 90° with the base of the skull. The experimental tests were carried out in dry medium and at room temperature in an electromechanical machine of the Model E1000 of the brand INSTRON ® . The analysis of the roughness parameters was evaluated in tracks. The laboratory results were satisfactory. The analysis of the histological synovial tissue in specimen were observed new vessels formation and synovial metaplasia like around prosthesis tissue. Based on 10 years of follow-up (2013 to 2023), with 9 patients and 17 surgeries performed, TMJ reconstruction using full custom TMJ prosthesis using PEEK Lt1 20% Ba, a new surgical technique was performed it is less traumatic than those used by other surgeons worldwide. The design of the prosthesis developed in customized PEEK Lt1 20%Ba presents an anatomical profile, where the center of gravity is preserved which can provide an ideal prosthesis, returning to the aspect physiological mandibular movements, providing less wear on the articular surface of the prosthesis.