Abstract.[Purpose] The purpose of this study was to examine changes in the carpal tunnels and median nerves appearing due to frequent movements of fingers by ultrasonography in young adults who frequently use smartphones.[Subjects] The subjects of this study were 20 young male and female adults who had no limitation in the range of movement of neck, shoulder, and arm joints, musculoskeletal disorder of the arm, or neurological symptoms such as paraesthesia and agreed to participate in the study.[Methods] The subjects who agreed to participate in this study were asked to use a smartphone for 30 minutes while maintaining comfortable sitting postures on a chair. They were asked to maintain the position of their shoulders comfortably while maintaining an angle of around 90° at the elbow. Some values measured before and after the experiment using a smartphone for 30 minutes were compared. The carpal tunnel was measured using ultrasonography.[Results] There were significant differences in median nerve circumference length, area of the median nerve area, distance between the highest point of the median nerve to the lunate, and distance between the bottom point of the median nerve to the lunate between before and after the experiment(p<0.05). [Conclusion] In conclusion, the use of smartphones for too long can be considered to adversely affect the wrist, and continued use can be considered to induce muscle fatigue.