“…Many articles 2,11‐13 addressed the effects of cryotherapy on tissue temperature. In response to temperature reduction, other physiological functions decreased: blood flow, 2,11,14,15 swelling, 2,4,10,11 metabolic functions, 7,16,17 and pain 7,18‐21 . Despite an incomplete understanding of all physiological responses to cold, a great deal of information has been ascertained that is important in understanding post‐surgical clinical responses to cryotherapy.…”